/* ── Design tokens ──────────────────────────────────────────────────────────── */
:root {
  --bg:        #05070f;
  --panel:     #090d1a;
  --card:      #0d1120;
  --elevated:  #121828;
  --border:    rgba(100,130,255,0.18);
  --glow:      rgba(80,110,255,0.35);
  --cyan:      #00d4ff;
  --cyan-d:    rgba(0,212,255,0.13);
  --violet:    #9d8fff;
  --violet-d:  rgba(157,143,255,0.13);
  --emerald:   #00e5a0;
  --emerald-d: rgba(0,229,160,0.11);
  --amber:     #ffb547;
  --amber-d:   rgba(255,181,71,0.11);
  --rose:      #ff4f6d;
  --rose-d:    rgba(255,79,109,0.11);
  --t1: #eef2ff;
  --t2: #96a8d8;
  --t3: #5f72a8;
  --t4: #2e3d6b;
  --sw: 256px;
  --hh: 54px;
  --r:  11px;
}

*, *::before, *::after { box-sizing: border-box; margin: 0; padding: 0; }
html { scroll-behavior: smooth; }
body {
  font-family: 'DM Sans', sans-serif;
  background: var(--bg);
  color: var(--t1);
  min-height: 100vh;
  overflow-x: hidden;
  font-size: 14px;
}
body::before {
  content: '';
  position: fixed; inset: 0;
  background: radial-gradient(ellipse 80% 60% at 60% 10%, rgba(124,111,255,0.04) 0%, transparent 70%);
  pointer-events: none; z-index: 0;
}

/* ── AUTH OVERLAY ───────────────────────────────────────────────────────────── */
body.auth-page { min-height: 100vh; background: var(--bg); }

#auth-overlay {
  min-height: 100vh;
  background: var(--bg);
  display: flex; align-items: flex-start; justify-content: center;
  padding: 40px 20px;
}

.auth-box {
  width: 100%; max-width: 440px;
  background: var(--panel);
  border: 1px solid var(--border);
  border-radius: 16px;
  padding: 40px;
}

/* Logo */
.auth-logo {
  display: flex; align-items: center; gap: 12px;
  margin-bottom: 36px; justify-content: center;
}
.auth-logo-icon {
  width: 56px; height: 56px;
  background: var(--elevated);
  border-radius: 12px;
  display: flex; align-items: center; justify-content: center;
  flex-shrink: 0;
  overflow: hidden;
  border: 1px solid var(--border);
}
.auth-logo-icon img {
  width: 100%; height: 100%; object-fit: contain;
  filter: invert(1) hue-rotate(180deg);
}
.auth-logo-txt {
  font-family: 'Outfit', sans-serif;
  font-size: 16px; font-weight: 800; line-height: 1.2;
  background: linear-gradient(90deg, var(--cyan), var(--violet));
  -webkit-background-clip: text; -webkit-text-fill-color: transparent;
  background-clip: text;
}

/* Text */
.auth-title {
  font-family: 'Outfit', sans-serif;
  font-size: 22px; font-weight: 700;
  color: var(--t1); margin-bottom: 6px; text-align: center;
}
.auth-sub {
  font-size: 13px; color: var(--t2);
  text-align: center; margin-bottom: 28px; line-height: 1.6;
}

/* Badge */
.auth-badge {
  display: flex; align-items: center; gap: 6px; justify-content: center;
  background: var(--cyan-d); color: var(--cyan);
  border: 1px solid rgba(0,212,255,0.18);
  border-radius: 20px; padding: 4px 12px;
  font-size: 11px; font-weight: 600;
  width: fit-content; margin: 0 auto 24px;
}
.auth-badge-dot {
  width: 6px; height: 6px; border-radius: 50%;
  background: var(--cyan); flex-shrink: 0;
}

/* Features grid */
.auth-features {
  display: grid; grid-template-columns: 1fr 1fr;
  gap: 8px; margin-bottom: 24px;
}
.auth-feat {
  background: var(--card); border: 1px solid var(--border);
  border-radius: 8px; padding: 10px 12px;
  font-size: 11px; color: var(--t2); line-height: 1.5;
  display: flex; align-items: flex-start; gap: 7px;
}
.auth-feat-dot {
  width: 6px; height: 6px; border-radius: 50%;
  background: var(--cyan); flex-shrink: 0; margin-top: 3px;
}

/* Form fields */
.auth-field { margin-bottom: 16px; }
.auth-field label {
  display: block; font-size: 11px; font-weight: 600;
  letter-spacing: .08em; text-transform: uppercase;
  color: var(--t1); margin-bottom: 6px;
}
.auth-optional { color: var(--t2); font-weight: 400; text-transform: none; }
.auth-required { color: var(--rose); font-size: 10px; text-transform: none; }
.auth-field input {
  width: 100%; height: 44px;
  background: var(--card); border: 1px solid rgba(80,110,255,0.30);
  border-radius: 8px; padding: 0 14px;
  color: var(--t1); font-family: 'DM Sans', sans-serif;
  font-size: 14px; outline: none;
  transition: border-color .18s;
}
.auth-field input:focus { border-color: var(--cyan); }
.auth-field input::placeholder { color: var(--t3); }
.auth-select {
  width: 100%; height: 44px;
  background: var(--card); border: 1px solid rgba(80,110,255,0.30);
  border-radius: 8px; padding: 0 14px;
  color: var(--t1); font-family: 'DM Sans', sans-serif;
  font-size: 14px; outline: none; cursor: pointer;
  appearance: none;
  background-image: url("data:image/svg+xml,%3Csvg xmlns='http://www.w3.org/2000/svg' width='12' height='12' viewBox='0 0 24 24' fill='none' stroke='%23687aaa' stroke-width='2.5' stroke-linecap='round' stroke-linejoin='round'%3E%3Cpolyline points='6 9 12 15 18 9'/%3E%3C/svg%3E");
  background-repeat: no-repeat;
  background-position: right 14px center;
  transition: border-color .18s;
}
.auth-select:focus { border-color: var(--cyan); }
.auth-select option, .auth-select optgroup { background: var(--panel); color: var(--t1); }

/* Consent block */
.auth-consent { margin-bottom: 18px; }
.auth-consent-box {
  background: rgba(80,110,255,0.06); border: 1px solid rgba(80,110,255,0.20);
  border-radius: 8px; margin-bottom: 12px;
}
.auth-consent-summary {
  display: flex; align-items: center; justify-content: space-between;
  padding: 11px 16px; cursor: pointer; list-style: none; user-select: none;
  gap: 10px;
}
.auth-consent-summary::-webkit-details-marker { display: none; }
.auth-consent-summary:hover { background: rgba(80,110,255,0.06); border-radius: 8px; }
.auth-consent-summary-left { display: flex; align-items: center; gap: 8px; flex-wrap: wrap; }
.auth-consent-summary-chevron {
  flex-shrink: 0; color: var(--t3); transition: transform .2s;
}
details.auth-consent-box[open] .auth-consent-summary-chevron { transform: rotate(90deg); }
.auth-consent-body { padding: 0 16px 14px; border-top: 1px solid rgba(80,110,255,0.15); padding-top: 12px; }
.auth-consent-badges {
  display: flex; gap: 6px;
}
.consent-badge {
  font-size: 10px; font-weight: 700; letter-spacing: .06em;
  padding: 2px 7px; border-radius: 4px;
  background: rgba(0,212,255,0.12); color: var(--cyan);
  border: 1px solid rgba(0,212,255,0.25);
}
.auth-consent-text {
  font-size: 12px; color: var(--t2); line-height: 1.6; margin: 0 0 8px;
}
.auth-consent-list {
  font-size: 12px; color: var(--t2); line-height: 1.7;
  margin: 0; padding-left: 18px;
}
.auth-consent-list li { margin-bottom: 2px; }
.auth-consent-list strong { color: var(--t1); }
.auth-consent-label {
  display: flex; align-items: flex-start; gap: 10px; cursor: pointer;
}
.auth-consent-label input[type="checkbox"] {
  width: 16px; height: 16px; min-width: 16px; margin-top: 2px;
  accent-color: var(--cyan); cursor: pointer;
}
.auth-consent-check-txt {
  font-size: 12px; color: var(--t2); line-height: 1.6;
}
.auth-consent-check-txt a { color: var(--cyan); text-decoration: none; }
.auth-consent-check-txt a:hover { text-decoration: underline; }

/* Button */
.auth-btn {
  width: 100%; height: 46px;
  background: linear-gradient(135deg, var(--cyan), var(--violet));
  border: none; border-radius: 8px;
  color: #05070f; font-family: 'Outfit', sans-serif;
  font-size: 14px; font-weight: 700; cursor: pointer;
  margin-top: 8px; transition: opacity .18s;
  letter-spacing: .02em;
}
.auth-btn:hover { opacity: .88; }

/* Divider */
.auth-divider {
  display: flex; align-items: center; gap: 12px;
  margin: 20px 0; color: var(--t3); font-size: 12px;
}
.auth-divider::before, .auth-divider::after {
  content: ''; flex: 1; height: 1px; background: var(--border);
}

/* Links */
.auth-link {
  text-align: center; font-size: 13px; color: var(--t2);
  margin-top: 20px;
}
.auth-link a {
  color: var(--cyan); text-decoration: none; font-weight: 600;
  cursor: pointer;
}
.auth-link a:hover { text-decoration: underline; }

/* Error / success messages */
.auth-error {
  background: var(--rose-d); border: 1px solid rgba(255,79,109,0.22);
  border-radius: 8px; padding: 10px 14px;
  font-size: 12px; color: var(--rose);
  margin-bottom: 16px;
}
.auth-success {
  background: var(--emerald-d); border: 1px solid rgba(0,229,160,0.20);
  border-radius: 8px; padding: 10px 14px;
  font-size: 12px; color: var(--emerald);
  margin-bottom: 16px;
}
.auth-success-center {
  text-align: center; padding: 20px 14px;
}
.auth-success-icon { font-size: 30px; margin-bottom: 10px; }
.auth-success-title { font-weight: 700; font-size: 14px; margin-bottom: 4px; }
.auth-success-body { color: var(--t2); font-size: 12px; line-height: 1.6; }
.auth-success-body strong { color: var(--t1); }

/* Back button */
.auth-back {
  background: none; border: 1px solid var(--border);
  border-radius: 8px; color: var(--t2); font-family: 'DM Sans', sans-serif;
  font-size: 13px; cursor: pointer; padding: 8px 16px;
  position: absolute; top: 20px; left: 20px;
  transition: all .15s;
  display: flex; align-items: center; gap: 6px;
  text-decoration: none;
}
.auth-back:hover { border-color: var(--glow); color: var(--t1); }

/* ── HEADER ─────────────────────────────────────────────────────────────────── */
header {
  position: fixed; top: 0; left: 0; right: 0; height: var(--hh);
  background: rgba(5,7,15,0.94); backdrop-filter: blur(20px);
  border-bottom: 1px solid var(--border);
  display: flex; align-items: center;
  padding: 0 18px 0 calc(var(--sw) + 18px);
  z-index: 100; gap: 12px;
}
.hid {
  font-family: 'JetBrains Mono', monospace;
  font-size: 12px; color: var(--cyan); letter-spacing: .06em;
}
.hright { margin-left: auto; display: flex; align-items: center; gap: 8px; }
.hdate {
  font-size: 11px; color: var(--t3);
  font-family: 'JetBrains Mono', monospace;
}
.hbtn {
  height: 30px; padding: 0 11px; border-radius: 7px;
  border: 1px solid var(--border); background: var(--card); color: var(--t2);
  font-size: 11px; cursor: pointer;
  display: flex; align-items: center; gap: 5px;
  transition: all .18s; font-family: 'DM Sans', sans-serif;
  text-decoration: none;
}
.hbtn:hover { border-color: var(--glow); color: var(--t1); }

/* ── SIDEBAR ─────────────────────────────────────────────────────────────────── */
#sb {
  position: fixed; top: var(--hh); left: 0; bottom: 0; width: var(--sw);
  background: var(--panel); border-right: 1px solid var(--border);
  overflow-y: auto; overflow-x: hidden; z-index: 90;
  padding-bottom: 20px;
  display: flex; flex-direction: column;
}
#sb::-webkit-scrollbar { width: 3px; }
#sb::-webkit-scrollbar-thumb { background: var(--border); border-radius: 2px; }
.sblogo {
  padding: 16px 18px 14px;
  display: flex; align-items: center; gap: 9px;
  border-bottom: 1px solid var(--border); margin-bottom: 6px;
  flex-shrink: 0;
}
.sblogo-icon {
  width: 42px; height: 42px;
  background: var(--elevated);
  border-radius: 9px;
  display: flex; align-items: center; justify-content: center;
  flex-shrink: 0;
  overflow: hidden;
  border: 1px solid var(--border);
}
.sblogo-icon img {
  width: 100%; height: 100%; object-fit: contain;
  filter: invert(1) hue-rotate(180deg);
}
.sblogo-txt {
  font-family: 'Outfit', sans-serif;
  font-size: 13px; font-weight: 800; line-height: 1.25;
  background: linear-gradient(90deg, var(--cyan), var(--violet));
  -webkit-background-clip: text; -webkit-text-fill-color: transparent;
  background-clip: text;
}
.sbsec { padding: 2px 10px; }
.sblabel {
  font-size: 9px; font-weight: 700; letter-spacing: .12em;
  text-transform: uppercase; color: var(--t2);
  padding: 10px 8px 5px; display: block;
}
.ni {
  display: flex; align-items: center; gap: 9px;
  padding: 7px 9px; border-radius: 7px; cursor: pointer;
  transition: all .14s; color: var(--t2);
  font-size: 12px; font-weight: 400;
  text-decoration: none; position: relative;
  white-space: nowrap; overflow: hidden;
}
.ni .ico {
  width: 14px; height: 14px;
  flex-shrink: 0;
  stroke: currentColor;
  fill: none;
}
.ni-user {
  overflow: hidden; text-overflow: ellipsis; white-space: nowrap; max-width: 160px;
}
.sb-account { margin-top: auto; border-top: 1px solid var(--border); padding-top: 6px; }
.ni:hover { background: rgba(80,110,255,0.06); color: var(--t1); }
.ni.active { background: rgba(0,212,255,0.07); color: var(--cyan); font-weight: 500; }
.ni.active::before {
  content: ''; position: absolute; left: 0; top: 50%;
  transform: translateY(-50%); width: 3px; height: 55%;
  background: var(--cyan); border-radius: 0 2px 2px 0;
}

/* ── SIDEBAR GROUPS (DNA / RNA collapsible) ──────────────────────────────────── */
.sb-group { border: none; margin: 0; }
.sb-group summary { list-style: none; }
.sb-group summary::-webkit-details-marker { display: none; }
.sb-group-hd {
  display: flex; align-items: center; gap: 9px;
  padding: 7px 9px; border-radius: 7px; cursor: pointer;
  color: var(--t1); font-size: 12px; font-weight: 600;
  letter-spacing: .04em; text-transform: uppercase;
  user-select: none; transition: background .14s;
}
.sb-group-hd:hover { background: rgba(80,110,255,0.06); }
.sb-group-hd .ico { width: 14px; height: 14px; flex-shrink: 0; stroke: var(--cyan); }
.sb-group-lbl { flex: 1; }
.sb-chevron { flex-shrink: 0; color: var(--t3); transition: transform .2s; }
.sb-group[open] > summary .sb-chevron { transform: rotate(90deg); }
.sb-group-body { padding-left: 8px; border-left: 1px solid var(--border); margin-left: 16px; margin-bottom: 4px; }

/* ── MAIN ────────────────────────────────────────────────────────────────────── */
main {
  margin-left: var(--sw); margin-top: var(--hh);
  padding: 28px 32px;
  min-height: calc(100vh - var(--hh));
  position: relative; z-index: 1;
}

/* Page header */
.ph { margin-bottom: 28px; }
.ph-title {
  font-family: 'Outfit', sans-serif;
  font-size: 24px; font-weight: 700;
  display: flex; align-items: center; gap: 10px; margin-bottom: 4px;
}
.ph-sub { color: var(--t2); font-size: 13px; }

/* Card */
.card {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--r); padding: 20px;
  transition: border-color .18s;
}
.card:hover { border-color: var(--glow); }
.ct {
  font-family: 'Outfit', sans-serif;
  font-size: 13px; font-weight: 700;
  margin-bottom: 14px;
  display: flex; align-items: center; gap: 7px;
}

/* ── REPORT COMPONENTS ──────────────────────────────────────────────────────── */

/* Alert banners */
.alert { border-radius: 10px; padding: 15px 18px; display: flex; align-items: flex-start; gap: 13px; margin-bottom: 20px; }
.alert-rose    { background: var(--rose-d);    border: 1px solid rgba(255,79,109,0.22); }
.alert-emerald { background: var(--emerald-d); border: 1px solid rgba(0,229,160,0.18); }
.alert-amber   { background: var(--amber-d);   border: 1px solid rgba(255,181,71,0.18); }
.alert-cyan    { background: var(--cyan-d);    border: 1px solid rgba(0,212,255,0.18); }
.alert-violet  { background: var(--violet-d);  border: 1px solid rgba(157,143,255,0.25); }
.alert-body { flex: 1; }
.alert-title { font-family: 'Outfit', sans-serif; font-size: 14px; font-weight: 700; margin-bottom: 4px; }
.alert-rose .alert-title    { color: var(--rose); }
.alert-emerald .alert-title { color: var(--emerald); }
.alert-amber .alert-title   { color: var(--amber); }
.alert-cyan .alert-title    { color: var(--cyan); }
.alert-violet .alert-title  { color: var(--violet); }
.alert p { font-size: 13px; line-height: 1.6; color: var(--t2); margin: 0; }

/* Stats grid */
.stat-grid { display: grid; gap: 12px; margin-bottom: 24px; }
.sg2 { grid-template-columns: repeat(2,1fr); }
.sg3 { grid-template-columns: repeat(3,1fr); }
.sg4 { grid-template-columns: repeat(4,1fr); }
.sg5 { grid-template-columns: repeat(5,1fr); }
@media (max-width: 900px) { .sg5 { grid-template-columns: repeat(3,1fr); } }


.stat-box { background: var(--elevated); border: 1px solid var(--border); border-radius: var(--r); padding: 15px 18px; }
.stat-lbl { font-size: 11px; color: var(--t2); margin-bottom: 5px; }
.stat-lbl[data-tip] { cursor: default; }
/* JS tooltip rendered in <body> — see app-end.ejs */
#stat-tooltip { position: fixed; background: #1a1f3a; color: #c8d4f0; font-size: 11px; font-weight: 400; line-height: 1.5; padding: 8px 12px; border-radius: 8px; border: 1px solid rgba(255,255,255,0.1); width: 220px; white-space: normal; text-align: left; pointer-events: none; z-index: 9999; box-shadow: 0 4px 16px rgba(0,0,0,0.5); opacity: 0; transition: opacity .15s; }
#stat-tooltip.visible { opacity: 1; }
.stat-val { font-family: 'Outfit', sans-serif; font-size: 28px; font-weight: 700; line-height: 1; color: var(--t1); }
.stat-val-r { color: var(--rose); }
.stat-val-a { color: var(--amber); }
.stat-val-e { color: var(--emerald); }
.stat-val-c { color: var(--cyan); }

/* Significance badges */
.sig { display: inline-flex; align-items: center; padding: 2px 8px; border-radius: 20px; font-size: 11px; font-weight: 600; white-space: nowrap; }
.sig-pathogenic  { background: var(--rose-d);    color: var(--rose);    border: 1px solid rgba(255,79,109,0.3); }
.sig-lp          { background: var(--amber-d);   color: var(--amber);   border: 1px solid rgba(255,181,71,0.3); }
.sig-vus         { background: var(--amber-d);   color: var(--amber);   border: 1px solid rgba(255,181,71,0.18); opacity:.85; }
.sig-conflicting { background: var(--violet-d);  color: var(--violet);  border: 1px solid rgba(124,111,255,0.25); }
.sig-benign      { background: var(--emerald-d); color: var(--emerald); border: 1px solid rgba(0,229,160,0.22); }
.sig-unknown     { background: var(--elevated);  color: var(--t2);      border: 1px solid var(--border); }

/* Source badge */
.src-badge { display: inline-flex; align-items: center; gap: 5px; padding: 2px 8px; border-radius: 20px; font-size: 10px; font-weight: 600; letter-spacing:.02em; margin-left: auto; }
.src-ai      { background: rgba(124,111,255,0.15); color: var(--violet); border: 1px solid rgba(124,111,255,0.28); }
.src-curated { background: var(--cyan-d); color: var(--cyan); border: 1px solid rgba(0,212,255,0.22); }
.src-low        { background: var(--elevated); color: var(--t3); border: 1px solid var(--border); }
.src-notcurated { background: rgba(255,181,71,0.12); color: var(--amber); border: 1px solid rgba(255,181,71,0.3); white-space: nowrap; }

/* SV section grouping */
.sv-section { margin-bottom: 24px; }
.sv-section-hd { display: flex; align-items: center; gap: 10px; padding: 10px 16px; background: var(--elevated); border-radius: 8px; border-left: 3px solid var(--border); margin-bottom: 10px; }
.sv-section-hd-r { border-left-color: var(--rose); }
.sv-section-hd-a { border-left-color: var(--amber); }
.sv-section-title { font-size: 11px; font-weight: 700; letter-spacing: .08em; text-transform: uppercase; flex: 1; }
.sv-section-hd-r .sv-section-title { color: var(--rose); }
.sv-section-hd-a .sv-section-title { color: var(--amber); }
.sv-section-count { font-size: 11px; font-weight: 700; padding: 2px 10px; border-radius: 20px; }
.sv-count-r { background: rgba(255,79,109,0.12); color: var(--rose); }
.sv-count-a { background: rgba(255,181,71,0.12); color: var(--amber); }

/* Variant cards */
.vcard { background: var(--card); border: 1px solid var(--border); border-radius: var(--r); overflow: hidden; margin-bottom: 12px; transition: border-color .18s; }
.vcard:hover { border-color: var(--glow); }
details.vcard > summary { list-style: none; outline: none; cursor: pointer; }
details.vcard > summary::-webkit-details-marker { display: none; }
details.vcard > summary::marker { display: none; }
.vcard-summary { padding: 13px 18px; border-bottom: 1px solid transparent; display: flex; align-items: center; gap: 10px; flex-wrap: nowrap; background: linear-gradient(135deg, rgba(124,111,255,0.10), rgba(0,212,255,0.05)); transition: background .15s; }
.vcard-summary:hover { background: linear-gradient(135deg, rgba(124,111,255,0.16), rgba(0,212,255,0.09)); }
.vcard-summary-r { background: linear-gradient(135deg, rgba(255,79,109,0.10), rgba(124,111,255,0.05)); }
.vcard-summary-r:hover { background: linear-gradient(135deg, rgba(255,79,109,0.16), rgba(124,111,255,0.09)); }
details.vcard[open] > .vcard-summary { border-bottom-color: var(--border); }
.vcard-gene { font-family: 'Outfit', sans-serif; font-size: 15px; font-weight: 700; flex-shrink: 0; }
.vcard-condition { flex: 1; font-size: 12px; color: var(--t2); overflow: hidden; text-overflow: ellipsis; white-space: nowrap; min-width: 0; padding: 0 8px; }
.vcard-stars { flex-shrink: 0; font-size: 10px; }
.vcard-hint { font-size: 10px; color: var(--t3); flex-shrink: 0; padding: 2px 8px; border: 1px solid var(--border); border-radius: 10px; white-space: nowrap; }
details.vcard[open] .vcard-hint { display: none; }
.vcard-chevron { flex-shrink: 0; transition: transform .2s; }
details.vcard[open] .vcard-chevron { transform: rotate(90deg); }
.vcard-head { padding: 15px 18px; border-bottom: 1px solid var(--border); display: flex; align-items: center; gap: 10px; flex-wrap: wrap; background: linear-gradient(135deg, rgba(124,111,255,0.12), rgba(0,212,255,0.06)); }
.vcard-head-r { background: linear-gradient(135deg, rgba(255,79,109,0.12), rgba(124,111,255,0.06)); }
.vcard-meta { background: var(--elevated); padding: 13px 18px; border-bottom: 1px solid var(--border); }
.vmeta-grid { display: grid; grid-template-columns: repeat(auto-fit, minmax(170px, 1fr)); gap: 8px; }
.vmeta-item { display: flex; align-items: center; gap: 7px; font-size: 12px; }
.vmeta-key { color: var(--t2); }
.vmeta-val { color: var(--t1); font-family: 'JetBrains Mono', monospace; font-size: 11px; }
.vcard-body { padding: 18px; }

/* Info panels inside variant cards */
.info-panel { border-radius: 8px; padding: 13px 15px; margin-bottom: 10px; }
.ip-blue   { background: rgba(0,212,255,0.06);   border-left: 3px solid var(--cyan); }
.ip-amber  { background: rgba(255,181,71,0.07);  border-left: 3px solid var(--amber); }
.ip-rose   { background: rgba(255,79,109,0.06);  border-left: 3px solid var(--rose); }
.ip-gray   { background: var(--elevated);        border-left: 3px solid var(--t3); }
.ip-emerald{ background: rgba(0,229,160,0.05);   border-left: 3px solid var(--emerald); }
.ip-title  { font-size: 11px; font-weight: 700; text-transform: uppercase; letter-spacing:.06em; margin-bottom: 6px; }
.ip-blue .ip-title    { color: var(--cyan); }
.ip-amber .ip-title   { color: var(--amber); }
.ip-rose .ip-title    { color: var(--rose); }
.ip-emerald .ip-title { color: var(--emerald); }
.ip-gray .ip-title    { color: var(--t2); }
.info-panel p { font-size: 13px; color: var(--t2); line-height: 1.6; margin: 0; }

/* Action cards */
.action-grid { display: grid; grid-template-columns: repeat(auto-fit, minmax(190px, 1fr)); gap: 10px; margin-top: 12px; }
.action-card { background: var(--elevated); border: 1px solid var(--border); border-radius: var(--r); padding: 13px; }
.ac-r { border-color: rgba(255,79,109,0.2); }
.ac-c { border-color: rgba(0,212,255,0.2); }
.ac-e { border-color: rgba(0,229,160,0.18); }
.ac-v { border-color: rgba(124,111,255,0.2); }
.ac-title { font-size: 10px; font-weight: 700; text-transform: uppercase; letter-spacing:.07em; margin-bottom: 8px; display: flex; align-items: center; gap: 6px; }
.ac-r .ac-title { color: var(--rose); }
.ac-c .ac-title { color: var(--cyan); }
.ac-e .ac-title { color: var(--emerald); }
.ac-v .ac-title { color: var(--violet); }
.action-card ul { padding: 0; margin: 0; list-style: none; }
.action-card li { font-size: 12px; color: var(--t2); padding: 3px 0 3px 14px; position: relative; line-height: 1.5; }
.action-card li::before { content: '›'; position: absolute; left: 0; color: var(--t3); }

/* Progress bars (ancestry) */
.prog-row { margin-bottom: 11px; }
.prog-label { display: flex; justify-content: space-between; margin-bottom: 4px; font-size: 13px; }
.prog-pct { font-family: 'JetBrains Mono', monospace; font-size: 12px; color: var(--t2); }
.prog-track { height: 6px; background: var(--elevated); border-radius: 3px; overflow: hidden; }
.prog-fill { height: 100%; border-radius: 3px; }
.pc-eur { background: var(--cyan); }
.pc-afr { background: #f97316; }
.pc-eas { background: var(--rose); }
.pc-csa { background: var(--emerald); }
.pc-amr { background: var(--violet); }
.pc-mid { background: var(--amber); }
.pc-oce { background: #06b6d4; }
.pc-other { background: var(--t3); }

/* Gene cards */
.gene-card { background: var(--elevated); border: 1px solid var(--border); border-radius: var(--r); padding: 15px; transition: border-color .15s; }
.gene-card:hover { border-color: var(--glow); }
.gene-name-row { display: flex; align-items: center; gap: 8px; flex-wrap: wrap; margin-bottom: 7px; }
.gene-name { font-family: 'Outfit', sans-serif; font-size: 14px; font-weight: 700; }
.gene-info { font-size: 12px; color: var(--t2); line-height: 1.5; }
.var-chips { display: flex; flex-wrap: wrap; gap: 4px; margin: 6px 0; }

/* PGX */
.pgx-badge { display: inline-flex; align-items: center; padding: 3px 9px; border-radius: 6px; font-size: 11px; font-weight: 600; font-family: 'JetBrains Mono', monospace; }
.pgx-poor         { background: var(--rose-d);    color: var(--rose);    border: 1px solid rgba(255,79,109,0.28); }
.pgx-intermediate { background: var(--amber-d);   color: var(--amber);   border: 1px solid rgba(255,181,71,0.28); }
.pgx-normal       { background: var(--emerald-d); color: var(--emerald); border: 1px solid rgba(0,229,160,0.22); }
.pgx-ultrarapid   { background: var(--violet-d);  color: var(--violet);  border: 1px solid rgba(124,111,255,0.28); }
.pgx-unknown      { background: var(--elevated);  color: var(--t2);      border: 1px solid var(--border); }
.prio-badge { display: inline-flex; align-items: center; padding: 2px 8px; border-radius: 20px; font-size: 10px; font-weight: 700; letter-spacing:.05em; text-transform: uppercase; }
.prio-critical { background: var(--rose-d);    color: var(--rose);    border: 1px solid rgba(255,79,109,0.3); }
.prio-high     { background: var(--amber-d);   color: var(--amber);   border: 1px solid rgba(255,181,71,0.3); }
.prio-moderate { background: var(--cyan-d);    color: var(--cyan);    border: 1px solid rgba(0,212,255,0.22); }
.prio-low      { background: var(--elevated);  color: var(--t2);      border: 1px solid var(--border); }
.prio-none     { background: var(--elevated);  color: var(--t3);      border: 1px solid var(--border); }

/* Report tables */
.rtable { width: 100%; border-collapse: collapse; font-size: 13px; }
.rtable th { font-size: 10px; font-weight: 700; text-transform: uppercase; letter-spacing:.07em; color: var(--t2); padding: 9px 13px; border-bottom: 1px solid var(--border); text-align: left; }
.rtable td { padding: 10px 13px; border-bottom: 1px solid var(--border); color: var(--t1); vertical-align: top; }
.rtable tr:last-child td { border-bottom: none; }
.rtable tr:hover td { background: rgba(100,130,255,0.06); }

/* Syndrome cards */
.syn-card { background: var(--elevated); border: 1px solid var(--border); border-radius: var(--r); padding: 20px; margin-bottom: 16px; transition: border-color .15s; }
.syn-card:hover { border-color: var(--glow); }
.syn-header { display: flex; align-items: center; gap: 10px; flex-wrap: wrap; margin-bottom: 10px; }
.syn-title { font-family: 'Outfit', sans-serif; font-size: 15px; font-weight: 700; }
.syn-desc { font-size: 13px; color: var(--t2); line-height: 1.65; margin-bottom: 16px; }
.syn-grid { display: grid; grid-template-columns: 1fr 1fr; gap: 14px; }
.syn-sec-lbl { font-size: 10px; font-weight: 700; text-transform: uppercase; letter-spacing:.08em; color: var(--t3); margin-bottom: 8px; }
.cancer-table { width: 100%; border-collapse: collapse; font-size: 12px; }
.cancer-table th { font-size: 10px; font-weight: 700; text-transform: uppercase; letter-spacing:.05em; color: var(--t3); padding: 6px 9px; border-bottom: 1px solid var(--border); text-align: left; }
.cancer-table td { padding: 7px 9px; border-bottom: 1px solid rgba(80,110,255,0.06); }
.cancer-table tr:last-child td { border-bottom: none; }
.cancer-table .high { color: var(--rose); font-weight: 600; }
.syn-surv li { font-size: 12px; color: var(--t2); padding: 3px 0 3px 16px; position: relative; line-height: 1.5; list-style: none; }
.syn-surv li::before { content: '✓'; position: absolute; left: 0; color: var(--emerald); font-size: 10px; top: 4px; }
.syn-source { font-size: 11px; color: var(--t3); margin-top: 12px; font-style: italic; }

/* PRS */
.prs-gauge { position: relative; height: 7px; border-radius: 4px; overflow: visible; background: linear-gradient(to right, var(--emerald), var(--amber), var(--rose)); margin-bottom: 5px; }
.prs-marker { position: absolute; top: -3px; width: 3px; height: 13px; background: var(--t1); border-radius: 2px; transform: translateX(-50%); }

/* Empty state */
.empty-state { text-align: center; padding: 54px 20px; }
.empty-ico { font-size: 38px; margin-bottom: 14px; opacity: .2; }
.empty-ttl { font-family: 'Outfit', sans-serif; font-size: 17px; font-weight: 600; margin-bottom: 7px; }
.empty-txt { color: var(--t2); font-size: 13px; max-width: 380px; margin: 0 auto; line-height: 1.65; }

/* Frequency */
.freq-vr { color: var(--rose);  font-size: 12px; font-weight: 600; }
.freq-r  { color: var(--amber); font-size: 12px; font-weight: 600; }
.freq-u  { color: var(--amber); font-size: 12px; opacity:.8; }
.freq-c  { color: var(--t3);    font-size: 12px; }
.freq-na { color: var(--t3);    font-size: 12px; font-style: italic; }

/* Section divider */
.sec-divider { border: none; border-top: 1px solid var(--border); margin: 24px 0; }
.sec-label { font-size: 10px; font-weight: 700; text-transform: uppercase; letter-spacing:.1em; color: var(--t3); margin-bottom: 14px; display: block; }
.two-col { display: grid; grid-template-columns: 1fr 1fr; gap: 16px; }
.three-col { display: grid; grid-template-columns: repeat(3, 1fr); gap: 14px; }

/* Low-evidence variants section */
.le-details { border: 1px solid var(--border); border-radius: 10px; overflow: hidden; }
.le-summary { display: flex; align-items: center; gap: 12px; padding: 14px 18px; cursor: pointer; user-select: none; background: var(--elevated); list-style: none; }
.le-summary::-webkit-details-marker { display: none; }
.le-summary:hover { background: var(--card); }
.le-badge { flex-shrink: 0; font-size: 10px; font-weight: 600; text-transform: uppercase; letter-spacing: .07em; color: var(--t3); background: var(--bg); border: 1px solid var(--border); padding: 3px 8px; border-radius: 20px; white-space: nowrap; }
.le-details[open] .le-summary { border-bottom: 1px solid var(--border); border-radius: 10px 10px 0 0; }
.le-details > div { padding: 16px; }

/* ClinVar star rating */
.clinvar-stars { display: inline-flex; gap: 2px; align-items: center; }
.cv-star-on  { color: #f59e0b; font-size: 11px; }
.cv-star-off { color: var(--border); font-size: 11px; }

/* ── ADMIN USER SWITCHER ─────────────────────────────────────────────────────── */
.usw { position: relative; }
.usw-btn {
  height: 30px; padding: 0 10px; border-radius: 7px;
  border: 1px solid rgba(157,143,255,0.35); background: var(--card); color: var(--violet);
  font-size: 11px; cursor: pointer;
  display: flex; align-items: center; gap: 6px;
  transition: all .18s; font-family: 'DM Sans', sans-serif;
  max-width: 200px;
}
.usw-btn:hover { border-color: var(--violet); color: var(--t1); }
.usw-btn span { overflow: hidden; text-overflow: ellipsis; white-space: nowrap; }
.usw-caret { flex-shrink: 0; transition: transform .2s; }
.usw-btn[aria-expanded="true"] .usw-caret { transform: rotate(180deg); }

.usw-panel {
  display: none; position: absolute; top: calc(100% + 6px); right: 0;
  width: 280px; background: var(--panel);
  border: 1px solid var(--border); border-radius: 10px;
  box-shadow: 0 8px 32px rgba(0,0,0,0.5);
  z-index: 500; overflow: hidden;
}
.usw-panel.visible { display: block; }
.usw-search-wrap { padding: 10px 10px 6px; border-bottom: 1px solid var(--border); }
.usw-search {
  width: 100%; height: 32px; background: var(--card);
  border: 1px solid var(--border); border-radius: 6px;
  padding: 0 10px; color: var(--t1); font-family: 'DM Sans', sans-serif;
  font-size: 12px; outline: none;
}
.usw-search:focus { border-color: var(--violet); }
.usw-search::placeholder { color: var(--t3); }
.usw-list { max-height: 260px; overflow-y: auto; padding: 6px; }
.usw-list::-webkit-scrollbar { width: 3px; }
.usw-list::-webkit-scrollbar-thumb { background: var(--border); border-radius: 2px; }
.usw-item {
  padding: 8px 10px; border-radius: 6px; cursor: pointer;
  font-size: 12px; color: var(--t1); line-height: 1.4;
  transition: background .12s;
}
.usw-item:hover { background: rgba(157,143,255,0.1); }
.usw-email { color: var(--t3); font-size: 11px; margin-left: 4px; }
.usw-loading { padding: 14px 10px; font-size: 12px; color: var(--t3); text-align: center; }

/* "Viewing as" banner below header */
.usw-banner {
  position: fixed; top: var(--hh); left: var(--sw); right: 0; z-index: 80;
  background: rgba(255,181,71,0.1); border-bottom: 1px solid rgba(255,181,71,0.25);
  color: var(--amber); font-size: 11px; padding: 5px 18px;
  display: flex; align-items: center; gap: 7px;
}
.usw-banner strong { color: var(--t1); }
/* Push main content down when banner is visible */
body:has(.usw-banner) main { margin-top: calc(var(--hh) + 29px); }
@media (max-width: 768px) {
  .usw-banner { left: 0; }
  body:has(.usw-banner) main { margin-top: calc(var(--hh) + 29px); }
}

/* ── RNA REPORT ──────────────────────────────────────────────────────────────── */

/* ── RNA test header metadata band ──────────────────────────────────────── */
.rna-ph-row {
  display:flex; align-items:flex-start; gap:16px; flex-wrap:wrap;
  margin-bottom:6px;
}
.rna-test-meta {
  flex:1 1 auto;
  display:grid; grid-template-columns:repeat(5,minmax(0,1fr)); gap:10px;
}
.rna-meta-item {
  background:linear-gradient(180deg, rgba(34,211,238,0.06), rgba(34,211,238,0.02));
  border:1px solid var(--border);
  border-left:3px solid var(--cyan);
  border-radius:var(--r);
  padding:12px 14px;
  min-width:0;
}
.rna-meta-lbl {
  font-size:10.5px; font-weight:600; letter-spacing:.08em; text-transform:uppercase;
  color:var(--t3); margin-bottom:6px; line-height:1.2;
}
.rna-meta-val {
  font-family:'Outfit', sans-serif; font-size:15px; font-weight:600;
  color:var(--t1); line-height:1.3; word-break:break-word;
}

/* ── Verdict banner ──────────────────────────────────────────────────────────── */
.rna-verdict {
  display: flex; flex-direction: column;
  border-radius: var(--r); border: 1px solid transparent;
  padding: 16px 22px; margin-bottom: 22px;
}
.rna-verdict-row { display: flex; align-items: center; gap: 16px; }
.rna-verdict-summary {
  margin-top: 12px; padding-top: 12px;
  border-top: 1px solid rgba(255,255,255,0.08);
  font-size: 13px; color: var(--t2); line-height: 1.55;
}
.rna-verdict-high     { background: linear-gradient(90deg, rgba(244,63,94,.13) 0%, rgba(244,63,94,.04) 55%, transparent 100%); border-color: rgba(244,63,94,.22); }
.rna-verdict-moderate { background: linear-gradient(90deg, rgba(251,191,36,.11) 0%, rgba(251,191,36,.03) 55%, transparent 100%); border-color: rgba(251,191,36,.2); }
.rna-verdict-low      { background: linear-gradient(90deg, rgba(34,211,238,.09) 0%, rgba(34,211,238,.02) 55%, transparent 100%); border-color: rgba(34,211,238,.18); }
.rna-verdict-normal   { background: linear-gradient(90deg, rgba(52,211,153,.09) 0%, rgba(52,211,153,.02) 55%, transparent 100%); border-color: rgba(52,211,153,.18); }

.rna-verdict-dot {
  width: 11px; height: 11px; border-radius: 50%; flex-shrink: 0;
}
.rna-verdict-high     .rna-verdict-dot { background: var(--rose);    box-shadow: 0 0 10px rgba(244,63,94,.55); }
.rna-verdict-moderate .rna-verdict-dot { background: var(--amber);   box-shadow: 0 0 10px rgba(251,191,36,.55); }
.rna-verdict-low      .rna-verdict-dot { background: var(--cyan);    box-shadow: 0 0 10px rgba(34,211,238,.45); }
.rna-verdict-normal   .rna-verdict-dot { background: var(--emerald); box-shadow: 0 0 10px rgba(52,211,153,.45); }

.rna-verdict-lbl { font-size: 10px; font-weight: 700; text-transform: uppercase; letter-spacing: .1em; color: var(--t3); margin-bottom: 3px; }
.rna-verdict-val { font-size: 17px; font-weight: 700; letter-spacing: -.02em; line-height: 1; }
.rna-verdict-high     .rna-verdict-val { color: var(--rose); }
.rna-verdict-moderate .rna-verdict-val { color: var(--amber); }
.rna-verdict-low      .rna-verdict-val { color: var(--cyan); }
.rna-verdict-normal   .rna-verdict-val { color: var(--emerald); }

.rna-verdict-sep  { width: 1px; height: 34px; background: var(--border); flex-shrink: 0; margin: 0 4px; }
.rna-verdict-desc { font-size: 13px; color: var(--t2); line-height: 1.55; }

/* ── Generic collapsible card pattern for RNA report sections ─────────────── */
.rna-collapse > summary { list-style: none; cursor: pointer; }
.rna-collapse > summary::-webkit-details-marker { display: none; }
.rna-collapse-summary {
  display: flex; align-items: center; gap: 8px;
  user-select: none;
}
.rna-collapse-chevron {
  margin-left: auto; color: var(--t3);
  transition: transform .2s ease;
  flex-shrink: 0;
}
.rna-collapse[open] > summary .rna-collapse-chevron { transform: rotate(90deg); }

/* Medical disclaimer collapse — looks like the old alert when expanded */
.rna-disclaimer-collapse {
  border: 1px solid rgba(251,191,36,0.3);
  border-radius: var(--r);
  background: rgba(251,191,36,0.05);
}
.rna-disclaimer-collapse > summary {
  padding: 12px 16px;
  color: var(--amber); font-weight: 600; font-size: 12.5px;
}
.rna-disclaimer-collapse[open] > summary { border-bottom: 1px solid rgba(251,191,36,0.25); }
.rna-disclaimer-body {
  padding: 12px 16px; font-size: 12.5px; color: var(--t2); line-height: 1.55;
}

/* ── Pathogen Profile (RNA reports — report.pathogen_profile) ─────────────── */
.pp-card {
  background: var(--card); border: 1px solid var(--border);
  border-left: 4px solid var(--border); border-radius: var(--r);
  padding: 18px 22px; margin-bottom: 22px;
  display: flex; flex-direction: column; gap: 14px;
}
.pp-card.pp-pass { border-left-color: var(--emerald); }
.pp-card.pp-warn { border-left-color: var(--amber); }
.pp-card.pp-high { border-left-color: var(--amber); }
.pp-card.pp-fail { border-left-color: var(--rose); }

/* Detection card has its own header (no flag pill / read composition) */
.pp-card-detections .pp-det-card-hd {
  display: flex; align-items: center; gap: 9px;
  margin-bottom: 4px;
}
.pp-card-detections .pp-det-card-hd svg { color: var(--rose); flex-shrink: 0; }
.pp-card-detections .pp-det-card-ttl {
  font-family: 'Outfit', sans-serif;
  font-size: 16px; font-weight: 700; color: var(--t1);
}

.pp-hd { display: flex; align-items: flex-start; gap: 14px; flex-wrap: wrap; }
.pp-flag {
  flex-shrink: 0;
  display: inline-flex; align-items: center; gap: 6px;
  padding: 5px 11px; border-radius: 6px;
  font-size: 12px; font-weight: 700; letter-spacing: .08em; text-transform: uppercase;
  border: 1px solid;
}
.pp-pass .pp-flag { color: var(--emerald); background: rgba(52,211,153,.10); border-color: rgba(52,211,153,.35); }
.pp-warn .pp-flag,
.pp-high .pp-flag { color: var(--amber);   background: rgba(251,191,36,.10); border-color: rgba(251,191,36,.35); }
.pp-fail .pp-flag { color: var(--rose);    background: rgba(244,63,94,.10);  border-color: rgba(244,63,94,.35); }

.pp-hd-body { flex: 1 1 280px; min-width: 0; }
.pp-title   { font-family: 'Outfit', sans-serif; font-size: 16px; font-weight: 700; color: var(--t1); }
.pp-sub     { font-size: 13px; color: var(--t2); line-height: 1.55; margin-top: 4px; }
.pp-validity {
  flex-shrink: 0; font-size: 11px; font-weight: 600; color: var(--t2);
  padding: 4px 10px; border-radius: 4px; background: var(--elevated); border: 1px solid var(--border);
  align-self: flex-start;
}

.pp-bar {
  display: flex; width: 100%; height: 14px;
  border-radius: 7px; overflow: hidden; background: var(--elevated);
}
.pp-bar > div { height: 100%; transition: width .2s ease; }
.pp-bar-human        { background: var(--emerald); }
.pp-bar-microbial    { background: var(--rose); }
.pp-bar-unclassified { background: var(--amber); }

.pp-legend { display: flex; flex-wrap: wrap; gap: 16px; font-size: 12px; color: var(--t2); }
.pp-leg-item { display: inline-flex; align-items: center; gap: 6px; }
.pp-leg-dot  { width: 10px; height: 10px; border-radius: 2px; display: inline-block; }
.pl-human        { background: var(--emerald); }
.pl-microbial    { background: var(--rose); }
.pl-unclassified { background: var(--amber); }

.pp-stats { display: grid; grid-template-columns: repeat(4, minmax(0, 1fr)); gap: 10px; }
.pp-stat {
  background: var(--elevated); border: 1px solid var(--border); border-radius: 8px;
  padding: 10px 12px; min-width: 0;
}
.pp-stat-lbl  { font-size: 10.5px; font-weight: 600; letter-spacing: .07em; text-transform: uppercase; color: var(--t3); margin-bottom: 4px; }
.pp-stat-val  { font-family: 'Outfit', sans-serif; font-size: 18px; font-weight: 700; color: var(--t1); line-height: 1.1; }
.pp-stat-meta { font-size: 11px; color: var(--t3); margin-top: 2px; }

.pp-summary { display: flex; flex-wrap: wrap; gap: 6px; }
.pp-badge {
  font-size: 10.5px; font-weight: 700; letter-spacing: .07em; text-transform: uppercase;
  padding: 4px 9px; border-radius: 4px; border: 1px solid;
}
.pp-badge.sev-critical { color: var(--rose);    background: rgba(244,63,94,.12); border-color: rgba(244,63,94,.4); }
.pp-badge.sev-high     { color: var(--rose);    background: rgba(244,63,94,.10); border-color: rgba(244,63,94,.3); }
.pp-badge.sev-moderate { color: var(--amber);   background: rgba(251,191,36,.10); border-color: rgba(251,191,36,.3); }
.pp-badge.sev-low      { color: var(--cyan);    background: rgba(34,211,238,.10); border-color: rgba(34,211,238,.3); }
.pp-badge.pp-badge-sub { color: var(--t3);      background: var(--elevated);      border-color: var(--border); }

.pp-sec-hd {
  display: flex; align-items: center; gap: 8px;
  font-family: 'Outfit', sans-serif; font-size: 13px; font-weight: 700;
  color: var(--t2); letter-spacing: .04em; text-transform: uppercase;
  margin-top: 4px;
}

.pp-det-list {
  display: grid; grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 10px;
  align-items: stretch;     /* equal height per row */
}
.pp-det-list .pp-det { height: 100%; }
.pp-det {
  background: var(--elevated); border: 1px solid var(--border); border-radius: 8px;
  border-left: 3px solid var(--border);
  padding: 12px 14px; display: flex; flex-direction: column; gap: 6px;
}
.pp-det.sev-critical { border-left-color: var(--rose);    background: linear-gradient(180deg, rgba(244,63,94,.05), var(--elevated)); }
.pp-det.sev-high     { border-left-color: var(--rose); }
.pp-det.sev-moderate { border-left-color: var(--amber); }
.pp-det.sev-low      { border-left-color: var(--cyan); }
.pp-det-hd { display: flex; align-items: center; gap: 10px; flex-wrap: wrap; }
.pp-det-sev {
  font-size: 10px; font-weight: 700; letter-spacing: .1em; text-transform: uppercase;
  padding: 2px 7px; border-radius: 3px;
}
.pp-det.sev-critical .pp-det-sev { color: var(--rose);  background: rgba(244,63,94,.15); }
.pp-det.sev-high     .pp-det-sev { color: var(--rose);  background: rgba(244,63,94,.12); }
.pp-det.sev-moderate .pp-det-sev { color: var(--amber); background: rgba(251,191,36,.12); }
.pp-det.sev-low      .pp-det-sev { color: var(--cyan);  background: rgba(34,211,238,.12); }
.pp-det-name { font-family: 'Outfit', sans-serif; font-size: 14.5px; font-weight: 700; color: var(--t1); }
.pp-det-flag {
  margin-left: auto; font-size: 9.5px; font-weight: 700; letter-spacing: .08em; text-transform: uppercase;
  color: var(--t3); padding: 2px 6px; border-radius: 3px; background: var(--card); border: 1px solid var(--border);
}
.pp-det-meta  { font-size: 12px; color: var(--t3); }
.pp-det-reads { font-size: 12.5px; color: var(--t2); }
.pp-det-reads-num { font-weight: 700; color: var(--t1); }
.pp-det-body  { font-size: 13px; color: var(--t2); line-height: 1.55; margin-top: 2px; }
.pp-det-notes { font-size: 11.5px; color: var(--t3); font-style: italic; margin-top: 2px; }

.pp-allclear {
  display: flex; align-items: center; gap: 8px;
  font-size: 13px; color: var(--t2);
  padding: 10px 14px; border-radius: 8px;
  background: rgba(52,211,153,.06); border: 1px solid rgba(52,211,153,.25);
}

.pp-details {
  border: 1px solid var(--border); border-radius: 8px; background: var(--elevated);
  padding: 4px 0;
}
.pp-details > summary {
  cursor: pointer; padding: 9px 14px; font-size: 12.5px; font-weight: 600;
  color: var(--t2); letter-spacing: .02em;
}
.pp-details[open] > summary { border-bottom: 1px solid var(--border); }
.pp-sub-explainer {
  padding: 10px 14px; margin: 4px 14px 6px;
  background: rgba(34,211,238,.05); border: 1px solid rgba(34,211,238,.2);
  border-radius: 6px;
  font-size: 11.5px; color: var(--t2); line-height: 1.55;
}
.pp-sub-explainer strong { color: var(--t1); font-weight: 600; }
.pp-sub-explainer em      { color: var(--t2); font-style: italic; }
.pp-sub-list, .pp-taxa-list { padding: 8px 14px 10px; display: flex; flex-direction: column; gap: 6px; }
.pp-sub-item, .pp-taxa-row {
  display: flex; align-items: center; gap: 10px; flex-wrap: wrap;
  font-size: 12px; padding: 5px 0;
}
.pp-sub-sev  {
  font-size: 9.5px; font-weight: 700; letter-spacing: .08em; text-transform: uppercase;
  padding: 2px 6px; border-radius: 3px; flex-shrink: 0;
}
.pp-sub-sev.sev-critical { color: var(--rose);  background: rgba(244,63,94,.12); }
.pp-sub-sev.sev-high     { color: var(--rose);  background: rgba(244,63,94,.10); }
.pp-sub-sev.sev-moderate { color: var(--amber); background: rgba(251,191,36,.10); }
.pp-sub-sev.sev-low      { color: var(--cyan);  background: rgba(34,211,238,.10); }
.pp-sub-name  { flex: 1 1 auto; color: var(--t1); font-weight: 500; }
.pp-sub-reads { color: var(--t3); flex-shrink: 0; }
.pp-taxa-rank {
  flex-shrink: 0; font-family: 'JetBrains Mono', monospace; font-size: 10.5px; font-weight: 700;
  color: var(--cyan); padding: 2px 6px; border-radius: 3px; background: rgba(34,211,238,.08); min-width: 26px; text-align: center;
}
.pp-taxa-name  { flex: 1 1 auto; color: var(--t1); }
.pp-taxa-reads { color: var(--t3); flex-shrink: 0; font-size: 11.5px; }

.pp-method {
  font-size: 11px; color: var(--t3); padding-top: 4px;
  border-top: 1px dashed var(--border); font-style: italic;
}

/* Reference cohort footer (shared across views) */
.rna-ref-cohort {
  display: flex; align-items: center; gap: 8px;
  font-size: 11.5px; color: var(--t3);
  padding: 10px 0 0; margin-top: 18px;
  border-top: 1px dashed var(--border);
}
.rna-ref-cohort strong { color: var(--t2); font-weight: 700; }

/* ── Sample decontamination card (DNA Overview) ────────────────────────── */
.decon-card {
  background: var(--card); border: 1px solid var(--border);
  border-left: 4px solid var(--border); border-radius: var(--r);
  padding: 18px 22px; margin-bottom: 22px;
  display: flex; flex-direction: column; gap: 14px;
}
.decon-pass { border-left-color: var(--emerald); }
.decon-fail { border-left-color: var(--rose); }
.decon-warn { border-left-color: var(--amber); }

.decon-hd { display: flex; align-items: flex-start; gap: 14px; }
.decon-flag {
  flex-shrink: 0;
  display: inline-flex; align-items: center; gap: 6px;
  padding: 5px 11px; border-radius: 6px;
  font-size: 12px; font-weight: 700; letter-spacing: .08em; text-transform: uppercase;
  border: 1px solid;
}
.decon-pass .decon-flag { color: var(--emerald); background: rgba(52,211,153,.10); border-color: rgba(52,211,153,.35); }
.decon-fail .decon-flag { color: var(--rose);    background: rgba(244,63,94,.10);  border-color: rgba(244,63,94,.35); }
.decon-warn .decon-flag { color: var(--amber);   background: rgba(251,191,36,.10); border-color: rgba(251,191,36,.35); }

.decon-hd-body { flex: 1 1 auto; min-width: 0; }
.decon-title   { font-family: 'Outfit', sans-serif; font-size: 16px; font-weight: 700; color: var(--t1); }
.decon-sub     { font-size: 13px; color: var(--t2); line-height: 1.55; margin-top: 4px; }

.decon-bar {
  display: flex; width: 100%; height: 14px;
  border-radius: 7px; overflow: hidden;
  background: var(--elevated);
}
.decon-bar > div { height: 100%; transition: width .2s ease; }
.decon-bar-human        { background: var(--emerald); }
.decon-bar-microbial    { background: var(--rose); }
.decon-bar-unclassified { background: var(--amber); }

.decon-legend { display: flex; flex-wrap: wrap; gap: 16px; font-size: 12px; color: var(--t2); }
.decon-leg-item { display: inline-flex; align-items: center; gap: 6px; }
.decon-leg-dot { width: 10px; height: 10px; border-radius: 2px; display: inline-block; }
.dl-human        { background: var(--emerald); }
.dl-microbial    { background: var(--rose); }
.dl-unclassified { background: var(--amber); }

.decon-stats {
  display: grid; grid-template-columns: repeat(5, minmax(0, 1fr)); gap: 10px;
}
.decon-stat {
  background: var(--elevated); border: 1px solid var(--border); border-radius: 8px;
  padding: 10px 12px; min-width: 0;
}
.decon-stat-lbl  { font-size: 10.5px; font-weight: 600; letter-spacing: .07em; text-transform: uppercase; color: var(--t3); margin-bottom: 4px; }
.decon-stat-val  { font-family: 'Outfit', sans-serif; font-size: 18px; font-weight: 700; color: var(--t1); line-height: 1.1; }
.decon-stat-meta { font-size: 11px; color: var(--t3); margin-top: 2px; }

/* ── Contamination QC card (Sample QC — Kraken2 on unmapped reads) ────────── */
/* Replaces the legacy decontamination card. Percentages here are over the
   sampled unmapped fraction (~1M reads), not the entire library. */
.cqc-card {
  background: var(--card); border: 1px solid var(--border);
  border-left: 4px solid var(--border); border-radius: var(--r);
  padding: 18px 22px; margin-bottom: 22px;
  display: flex; flex-direction: column; gap: 14px;
}
.cqc-pass { border-left-color: var(--emerald); }
.cqc-warn { border-left-color: var(--amber); }
.cqc-fail { border-left-color: var(--rose); }

.cqc-hd { display: flex; align-items: flex-start; gap: 14px; }
.cqc-flag {
  flex-shrink: 0;
  display: inline-flex; align-items: center; gap: 6px;
  padding: 5px 11px; border-radius: 6px;
  font-size: 12px; font-weight: 700; letter-spacing: .08em; text-transform: uppercase;
  border: 1px solid;
}
.cqc-pass .cqc-flag { color: var(--emerald); background: rgba(52,211,153,.10); border-color: rgba(52,211,153,.35); }
.cqc-warn .cqc-flag { color: var(--amber);   background: rgba(251,191,36,.10); border-color: rgba(251,191,36,.35); }
.cqc-fail .cqc-flag { color: var(--rose);    background: rgba(244,63,94,.10);  border-color: rgba(244,63,94,.35); }

.cqc-hd-body { flex: 1 1 auto; min-width: 0; }
.cqc-title   { font-family: 'Outfit', sans-serif; font-size: 16px; font-weight: 700; color: var(--t1); }
.cqc-tool    { font-size: 12px; font-weight: 500; color: var(--t3); margin-left: 4px; letter-spacing: 0; }
.cqc-sub     { font-size: 13px; color: var(--t2); line-height: 1.55; margin-top: 4px; }

.cqc-stats {
  display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 10px;
}
.cqc-stat {
  position: relative;
  background: var(--elevated); border: 1px solid var(--border); border-radius: 8px;
  padding: 10px 36px 10px 12px; min-width: 0;
}
.cqc-stat-lbl  { font-size: 10.5px; font-weight: 600; letter-spacing: .07em; text-transform: uppercase; color: var(--t3); margin-bottom: 4px; }
.cqc-stat-val  { font-family: 'Outfit', sans-serif; font-size: 18px; font-weight: 700; color: var(--t1); line-height: 1.1; }
.cqc-stat-meta { font-size: 11px; color: var(--t3); margin-top: 2px; }
.cqc-stat .fastp-tip-btn { position: absolute; top: 10px; right: 10px; }

/* Composition bar — stacked horizontal segments, one per category */
.cqc-bar {
  display: flex; width: 100%; height: 16px;
  border-radius: 8px; overflow: hidden;
  background: var(--elevated);
}
.cqc-bar-seg { height: 100%; transition: width .2s ease; }
/* Category colours — friendly chunk first, microbial classes graded by concern */
.cqc-bar-unclassified { background: var(--emerald); }
.cqc-bar-human        { background: var(--cyan); }
.cqc-bar-bacterial    { background: var(--amber); }
.cqc-bar-viral        { background: var(--rose); }
.cqc-bar-fungal       { background: var(--violet); }
.cqc-bar-archaeal     { background: var(--t3); }
.cqc-bar-other-euk    { background: var(--t4); }

.cqc-breakdown { display: flex; flex-direction: column; gap: 6px; }
.cqc-cat {
  display: grid;
  grid-template-columns: 14px minmax(140px, 1fr) 70px 1fr auto;
  gap: 12px; align-items: center;
  padding: 8px 12px; border-radius: 6px;
  background: var(--elevated); border: 1px solid var(--border);
}
.cqc-cat-dot { width: 12px; height: 12px; border-radius: 3px; display: inline-block; }
.cqc-cat-lbl   { font-size: 13px; font-weight: 600; color: var(--t1); }
.cqc-cat-pct   { font-family: 'Outfit', sans-serif; font-size: 14px; font-weight: 700; color: var(--t1); font-variant-numeric: tabular-nums; }
.cqc-cat-reads { font-size: 12px; color: var(--t3); font-variant-numeric: tabular-nums; }

.cqc-empty-bam {
  display: flex; align-items: center; gap: 10px;
  padding: 12px 16px; border-radius: 8px;
  background: rgba(52,211,153,0.06);
  border: 1px solid rgba(52,211,153,0.2);
  font-size: 13px; color: var(--t2);
}

/* Top-taxa expandable list */
.cqc-taxa-details > summary { list-style: none; cursor: pointer; user-select: none; }
.cqc-taxa-details > summary::-webkit-details-marker { display: none; }
.cqc-taxa-summary {
  display: inline-flex; align-items: center; gap: 8px;
  font-size: 12px; font-weight: 600; color: var(--cyan);
  letter-spacing: .03em; padding: 4px 0;
}
.cqc-taxa-chevron { transition: transform .2s ease; flex-shrink: 0; }
.cqc-taxa-details[open] > summary .cqc-taxa-chevron { transform: rotate(90deg); }
.cqc-taxa-explainer {
  margin-top: 10px; padding: 10px 14px;
  font-size: 12px; color: var(--t2); line-height: 1.55;
  background: var(--elevated); border: 1px dashed var(--border); border-radius: 6px;
}
.cqc-taxa-explainer strong { color: var(--t1); font-weight: 600; }
.cqc-taxa-list { margin-top: 10px; display: flex; flex-direction: column; gap: 5px; }
.cqc-taxa-row {
  display: grid;
  grid-template-columns: 30px 1fr auto auto;
  gap: 12px; align-items: center;
  padding: 6px 12px; border-radius: 4px;
  background: var(--elevated);
  font-size: 12.5px;
}
.cqc-taxa-rank  { font-size: 10.5px; font-weight: 700; color: var(--t3); letter-spacing: .04em; text-align: center; }
.cqc-taxa-name  { color: var(--t1); font-style: italic; }
.cqc-taxa-reads { font-family: 'Outfit', sans-serif; font-size: 12px; color: var(--t2); font-variant-numeric: tabular-nums; white-space: nowrap; }
.cqc-taxa-pct   { font-family: 'Outfit', sans-serif; font-size: 12px; font-weight: 700; color: var(--t1); font-variant-numeric: tabular-nums; white-space: nowrap; min-width: 56px; text-align: right; }

/* ── fastp QC card (DNA Overview — sequencing/library QC) ──────────────────── */
.fastp-card {
  background: var(--card); border: 1px solid var(--border);
  border-left: 4px solid var(--border); border-radius: var(--r);
  padding: 18px 22px; margin-bottom: 22px;
  display: flex; flex-direction: column; gap: 14px;
}
.fastp-pass { border-left-color: var(--emerald); }
.fastp-warn { border-left-color: var(--amber); }
.fastp-fail { border-left-color: var(--rose); }

.fastp-hd { display: flex; align-items: flex-start; gap: 14px; }
.fastp-flag {
  flex-shrink: 0;
  display: inline-flex; align-items: center; gap: 6px;
  padding: 5px 11px; border-radius: 6px;
  font-size: 12px; font-weight: 700; letter-spacing: .08em; text-transform: uppercase;
  border: 1px solid;
}
.fastp-pass .fastp-flag { color: var(--emerald); background: rgba(52,211,153,.10); border-color: rgba(52,211,153,.35); }
.fastp-warn .fastp-flag { color: var(--amber);   background: rgba(251,191,36,.10); border-color: rgba(251,191,36,.35); }
.fastp-fail .fastp-flag { color: var(--rose);    background: rgba(244,63,94,.10);  border-color: rgba(244,63,94,.35); }

.fastp-hd-body { flex: 1 1 auto; min-width: 0; }
.fastp-title   { font-family: 'Outfit', sans-serif; font-size: 16px; font-weight: 700; color: var(--t1); }
.fastp-tool    { font-size: 12px; font-weight: 500; color: var(--t3); letter-spacing: 0; text-transform: lowercase; margin-left: 4px; }
.fastp-sub     { font-size: 13px; color: var(--t2); line-height: 1.55; margin-top: 4px; }

.fastp-metrics { display: flex; flex-direction: column; gap: 6px; }
.fastp-row {
  display: grid;
  grid-template-columns: minmax(160px, 0.8fr) minmax(180px, 1.2fr) 1fr auto;
  gap: 14px; align-items: center;
  padding: 8px 12px; border-radius: 6px;
  background: var(--elevated);
  border: 1px solid var(--border);
}
.fastp-row-lbl  { font-size: 11.5px; font-weight: 600; letter-spacing: .04em; color: var(--t3); text-transform: uppercase; }
.fastp-row-val  { font-family: 'Outfit', sans-serif; font-size: 15px; font-weight: 700; color: var(--t1); font-variant-numeric: tabular-nums; }
.fastp-row-meta { font-size: 12px; color: var(--t3); font-variant-numeric: tabular-nums; }

/* ? button at the end of each row — click toggles a floating explanation. */
.fastp-tip-btn {
  display: inline-flex; align-items: center; justify-content: center;
  width: 20px; height: 20px; border-radius: 50%;
  font-size: 12px; font-weight: 700; line-height: 1;
  color: var(--t3);
  background: var(--card); border: 1px solid var(--border);
  cursor: pointer;
  transition: color .15s ease, border-color .15s ease, background .15s ease;
  flex-shrink: 0; padding: 0;
}
.fastp-tip-btn:hover { color: var(--cyan); border-color: var(--cyan); }
.fastp-tip-btn:focus { outline: none; color: var(--cyan); border-color: var(--cyan); box-shadow: 0 0 0 2px rgba(34,211,238,0.18); }
.fastp-tip-btn.is-open {
  color: var(--bg); background: var(--cyan); border-color: var(--cyan);
}

/* Floating explanation popup — body-level, escapes any stacking context. */
.fastp-tip-popup {
  max-width: 320px;
  padding: 12px 14px;
  font-size: 12.5px; line-height: 1.55; color: var(--t1);
  background: var(--card);
  border: 1px solid var(--cyan);
  border-radius: 8px;
  box-shadow: 0 8px 24px rgba(0,0,0,0.45), 0 0 0 4px rgba(34,211,238,0.06);
  pointer-events: none;  /* The script handles outside-clicks; popup doesn't intercept */
}

/* Expandable details */
.fastp-details > summary { list-style: none; cursor: pointer; user-select: none; }
.fastp-details > summary::-webkit-details-marker { display: none; }
.fastp-details-summary {
  display: inline-flex; align-items: center; gap: 8px;
  font-size: 12px; font-weight: 600; color: var(--cyan);
  letter-spacing: .03em; padding: 4px 0;
}
.fastp-details-chevron { transition: transform .2s ease; flex-shrink: 0; }
.fastp-details[open] > summary .fastp-details-chevron { transform: rotate(90deg); }
.fastp-details-body { margin-top: 10px; display: flex; flex-direction: column; gap: 6px; }

/* ── Sample reliability gate (RNA — when sample_quality is degraded) ──────── */
/* The pipeline team's guidance: when sample is degraded, banner the report and
   visually downweight everything *except* the gate banner and the pathogen
   profile cards. Pathogen high-burden detections (≥1000 reads) and metadata
   are trustworthy independently of signature quality. */
.rna-degraded-gate {
  display: flex; align-items: flex-start; gap: 14px;
  padding: 16px 20px;
  background: linear-gradient(90deg, rgba(244,63,94,.16) 0%, rgba(244,63,94,.06) 70%, transparent 100%);
  border: 1px solid rgba(244,63,94,.32);
  border-left: 4px solid var(--rose);
  border-radius: var(--r);
  margin-bottom: 18px;
  color: var(--t1);
}
.rna-degraded-ico  { color: var(--rose); flex-shrink: 0; margin-top: 2px; }
.rna-degraded-body { flex: 1; display: flex; flex-direction: column; gap: 6px; }
.rna-degraded-ttl  { font-size: 15px; font-weight: 700; color: var(--rose); letter-spacing: .01em; }
.rna-degraded-txt  { font-size: 13px; color: var(--t1); line-height: 1.55; }
.rna-degraded-txt strong { color: var(--rose); }
.rna-degraded-meta {
  display: flex; flex-wrap: wrap; gap: 14px;
  font-size: 11.5px; color: var(--t3); margin-top: 4px;
}
.rna-degraded-meta strong { color: var(--t2); font-weight: 600; }

/* When the report is in degraded mode, downweight everything visually except
   the gate banner and the pathogen profile cards (containing high-burden
   detections + metadata). The disclaimer + reference footer stay readable too. */
.rna-report[data-degraded="1"] > * { opacity: 0.55; transition: opacity .2s ease; }
.rna-report[data-degraded="1"] > .rna-degraded-gate,
.rna-report[data-degraded="1"] > .pp-card,
.rna-report[data-degraded="1"] > .rna-collapse,
.rna-report[data-degraded="1"] > .rna-ref-cohort { opacity: 1; }

/* Within the pathogen detections card, sub-1000-read items get dimmed further
   (they fall under the "don't rely on" guidance). */
.pp-det.pp-det-low-burden {
  opacity: 0.55;
  position: relative;
}
.pp-det-burden-flag {
  display: inline-block;
  font-size: 10px; font-weight: 700; letter-spacing: .07em; text-transform: uppercase;
  color: var(--t3);
  background: var(--elevated);
  border: 1px dashed var(--border);
  padding: 2px 8px; border-radius: 4px;
  margin-bottom: 6px;
}

/* Calibration caveat badge — shown on z-rows when healthy_sd < 0.05 means
   the z-magnitude is inflated. Also greys the magnitude text so the direction
   (encoded in the marker colour + the sub-label) reads as the headline. */
.rvs-zrow-multi.has-caveat .rvs-zrow-val { color: var(--t3); font-weight: 500; }
.rvs-caveat {
  display: inline-block;
  margin-left: 6px;
  font-size: 9.5px; font-weight: 700; letter-spacing: .05em;
  color: var(--amber);
  background: rgba(251,191,36,.10);
  border: 1px solid rgba(251,191,36,.28);
  padding: 1px 6px; border-radius: 3px;
  vertical-align: middle;
  white-space: nowrap;
  cursor: help;
}

/* ── Pipeline summary cards (Priority Findings + Recommended Investigations) ── */
.rsum-grid {
  display: grid; grid-template-columns: 1fr 1fr; gap: 14px;
  margin-bottom: 22px;
}
.rsum-card {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--r); padding: 16px 18px 14px;
  border-left: 4px solid var(--cyan);
  display: flex; flex-direction: column; gap: 8px;
}
.rsum-card.kind-priority { border-left-color: var(--amber); }
.rsum-card.kind-invest   { border-left-color: var(--cyan); }
.rsum-hd {
  display: flex; align-items: center; gap: 8px;
  font-size: 11px; font-weight: 700; letter-spacing: .09em; text-transform: uppercase;
  color: var(--t2);
}
.rsum-card.kind-priority .rsum-hd { color: var(--amber); }
.rsum-card.kind-invest   .rsum-hd { color: var(--cyan); }
.rsum-ttl   { flex: 1; }
.rsum-count {
  display: inline-flex; align-items: center; justify-content: center;
  min-width: 22px; padding: 2px 7px; border-radius: 999px;
  font-size: 10.5px; font-weight: 700;
  background: var(--elevated); color: var(--t2);
  border: 1px solid var(--border);
}
.rsum-list {
  list-style: none; padding: 0; margin: 4px 0 0;
  display: flex; flex-direction: column; gap: 8px;
}
.rsum-list li {
  position: relative; padding-left: 18px;
  font-size: 13px; color: var(--t1); line-height: 1.55;
}
.rsum-list li::before {
  content: '•'; position: absolute; left: 4px; top: 0;
  font-weight: 700;
}
.rsum-card.kind-priority .rsum-list li::before { color: var(--amber); }
.rsum-card.kind-invest   .rsum-list li::before { color: var(--cyan); }

/* ── Per-section detail cards (Infection / Inflammation / Cancer / Age / Landscape) ── */
.rna-sections {
  display: grid; grid-template-columns: 1fr 1fr; gap: 14px; margin-bottom: 24px;
}
.rsec-card {
  background: var(--card); border: 1px solid var(--border);
  border-left: 4px solid var(--border); border-radius: var(--r);
  padding: 16px 18px 14px;
  display: flex; flex-direction: column; gap: 12px;
  /* Make the Immune Landscape card span full width so its cell-composition
     bars have horizontal room. Achieved via inline span class below. */
}
.rsec-card.rsec-span-full { grid-column: 1 / -1; }

.rsec-card.flag-normal { border-left-color: var(--emerald); }
.rsec-card.flag-watch  { border-left-color: var(--amber); }
.rsec-card.flag-alert  { border-left-color: var(--rose); }
.rsec-card.flag-low    { border-left-color: var(--cyan); }
.rsec-card.flag-info   { border-left-color: var(--border); }

.rsec-hd {
  display: flex; align-items: center; gap: 10px;
  padding-bottom: 10px; border-bottom: 1px solid var(--border);
}
.rsec-ico { flex-shrink: 0; color: var(--t2); }
.rsec-ttl {
  font-size: 13px; font-weight: 700; color: var(--t1);
  letter-spacing: .02em; flex: 1;
}
.rsec-meta { display: flex; align-items: center; gap: 6px; flex-shrink: 0; }

.rsec-conf {
  font-size: 10px; font-weight: 600; letter-spacing: .04em;
  padding: 3px 8px; border-radius: 4px;
  background: var(--elevated); color: var(--t3);
  border: 1px solid var(--border); white-space: nowrap;
}
.rsec-conf.conf-high   { background: rgba(52,211,153,.10); color: var(--emerald); border-color: rgba(52,211,153,.25); }
.rsec-conf.conf-medium { background: rgba(251,191,36,.08); color: var(--amber);   border-color: rgba(251,191,36,.22); }
.rsec-conf.conf-low    { background: rgba(244,63,94,.08);  color: var(--rose);    border-color: rgba(244,63,94,.22); }

.rsec-flag {
  font-size: 10px; font-weight: 700; letter-spacing: .08em; text-transform: uppercase;
  padding: 3px 8px; border-radius: 4px; white-space: nowrap;
}
.rsec-flag.flag-normal { background: rgba(52,211,153,.12); color: var(--emerald); }
.rsec-flag.flag-watch  { background: rgba(251,191,36,.12); color: var(--amber); }
.rsec-flag.flag-alert  { background: rgba(244,63,94,.12);  color: var(--rose); }
.rsec-flag.flag-low    { background: rgba(34,211,238,.12); color: var(--cyan); }
.rsec-flag.flag-info   { background: var(--elevated);       color: var(--t3); }

.rsec-body { display: flex; flex-direction: column; gap: 12px; }

.rsec-subhd {
  font-size: 11px; font-weight: 700; letter-spacing: .07em; text-transform: uppercase;
  color: var(--t3); margin-top: 4px;
}

/* Pills row (bacterial/viral + sepsis endotype) */
.rsec-pills { display: flex; flex-wrap: wrap; gap: 14px; }
.rsec-pillbox {
  display: flex; flex-direction: column; gap: 6px;
  padding: 10px 14px; background: var(--elevated);
  border: 1px solid var(--border); border-radius: 8px;
  min-width: 160px; flex: 1 1 200px;
}
.rsec-pillbox-lbl { font-size: 10px; font-weight: 700; letter-spacing: .08em; text-transform: uppercase; color: var(--t3); }
.rsec-pillbox-sub { font-size: 11px; color: var(--t3); margin-top: 2px; }
.rsec-pill {
  display: inline-block; padding: 4px 12px; border-radius: 6px;
  font-size: 13px; font-weight: 700; letter-spacing: .04em;
  align-self: flex-start;
}
.rsec-pill.bv-viral     { background: rgba(34,211,238,.14);  color: var(--cyan);    border: 1px solid rgba(34,211,238,.32); }
.rsec-pill.bv-bacterial { background: rgba(244,63,94,.14);   color: var(--rose);    border: 1px solid rgba(244,63,94,.32); }
.rsec-pill.bv-mixed     { background: rgba(139,92,246,.14);  color: var(--violet);  border: 1px solid rgba(139,92,246,.32); }
.rsec-pill.bv-none      { background: var(--elevated);        color: var(--t3);     border: 1px solid var(--border); }
.rsec-pill.srs-srs1     { background: rgba(244,63,94,.14);   color: var(--rose);    border: 1px solid rgba(244,63,94,.32); }
.rsec-pill.srs-srs2     { background: rgba(251,191,36,.12);  color: var(--amber);   border: 1px solid rgba(251,191,36,.28); }

/* Stat grid */
.rsec-stats {
  display: grid; grid-template-columns: repeat(auto-fit, minmax(140px, 1fr));
  gap: 10px;
}
.rsec-stat {
  padding: 12px 14px; background: var(--elevated);
  border: 1px solid var(--border); border-radius: 8px;
}
.rsec-stat-wide { grid-column: 1 / -1; }
.rsec-stat-lbl  { font-size: 10.5px; font-weight: 700; letter-spacing: .07em; text-transform: uppercase; color: var(--t3); margin-bottom: 5px; }
.rsec-stat-val  { font-family: 'Outfit', sans-serif; font-size: 18px; font-weight: 700; color: var(--t1); line-height: 1.1; font-variant-numeric: tabular-nums; }
.rsec-stat-val.rsec-normal { color: var(--emerald); }
.rsec-stat-val.rsec-watch  { color: var(--amber); }
.rsec-stat-val.rsec-alert  { color: var(--rose); }
.rsec-stat-val.rsec-low    { color: var(--cyan); }
.rsec-stat-sub  { font-size: 11px; color: var(--t3); margin-top: 4px; line-height: 1.45; }

/* Notes list (pipeline-emitted free-text findings) */
.rsec-notes {
  list-style: none; padding: 0; margin: 0;
  display: flex; flex-direction: column; gap: 6px;
}
.rsec-notes li {
  position: relative; padding-left: 16px;
  font-size: 12.5px; color: var(--t2); line-height: 1.6;
}
.rsec-notes li::before {
  content: '•'; position: absolute; left: 4px; top: 0;
  color: var(--t3); font-weight: 700;
}

.rsec-disclaimer {
  font-size: 11.5px; color: var(--t3); line-height: 1.5;
  padding-top: 8px; border-top: 1px dashed var(--border);
}

/* ── RNA VISUAL SUMMARY (lay mode charts) ────────────────────────────────────── */
.rna-visual-summary {
  display: grid; grid-template-columns: 1fr 1fr; gap: 14px; margin-bottom: 24px;
}
.rvs-span-full { grid-column: 1 / -1; }

.rvs-card {
  background: var(--card); border: 1px solid var(--border);
  border-radius: var(--r); padding: 16px 18px 14px;
}

/* Sample-Quality banner — colour matches the actual quality status, never
   green when something fell outside the normal range. The icon stroke uses
   currentColor so it inherits the variant colour set below. */
.rvs-quality-note {
  display: flex; align-items: flex-start; gap: 8px;
  font-size: 13px; color: var(--t1); line-height: 1.55;
  border: 1px solid; border-radius: 8px; padding: 10px 12px;
  margin-bottom: 14px;
}
.rvs-quality-note svg { flex-shrink: 0; margin-top: 1px; }
.rvs-quality-note-ok {
  background: rgba(0, 229, 160, 0.07);
  border-color: rgba(0, 229, 160, 0.2);
}
.rvs-quality-note-ok svg { color: var(--emerald); }
.rvs-quality-note-warn {
  background: rgba(255, 181, 71, 0.08);
  border-color: rgba(255, 181, 71, 0.28);
}
.rvs-quality-note-warn svg { color: var(--amber); }

.rvs-card-hd {
  display: flex; align-items: center; gap: 7px;
  font-size: 11px; font-weight: 700; text-transform: uppercase;
  letter-spacing: .07em; color: var(--t3);
  margin-bottom: 14px; padding-bottom: 10px;
  border-bottom: 1px solid var(--border);
}
.rvs-card-hint { font-size: 10px; font-weight: 400; text-transform: none; letter-spacing: 0; color: var(--t2); margin-left: 2px; }

.rvs-rows { display: flex; flex-direction: column; gap: 12px; }
.rvs-row  {}
.rvs-row-top { display: flex; justify-content: space-between; align-items: center; margin-bottom: 6px; }
.rvs-label   { font-size: 13px; color: var(--t2); }
.rvs-value   { font-size: 13px; font-weight: 700; }

/* Status colours for values */
.rvs-normal { color: var(--emerald); }
.rvs-watch  { color: var(--amber);   }
.rvs-alert  { color: var(--rose);    }
.rvs-low    { color: var(--rose);    }
.rvs-high   { color: var(--amber);   }

/* Track: shared by both marker bars and fill bars */
.rvs-track {
  position: relative; height: 8px;
  background: var(--elevated); border-radius: 4px;
  overflow: visible;
}

/* Reference zone — green band showing the normal range */
.rvs-refzone {
  position: absolute; top: 0; height: 100%;
  background: rgba(0, 229, 160, 0.18);
  border-left:  1px solid rgba(0, 229, 160, 0.35);
  border-right: 1px solid rgba(0, 229, 160, 0.35);
  pointer-events: none; z-index: 1;
  border-radius: 1px;
}

/* Value marker — vertical line at the actual measurement position */
.rvs-marker {
  position: absolute; top: -4px;
  width: 3px; height: calc(100% + 8px);
  border-radius: 2px; z-index: 3;
  transform: translateX(-50%);
}
.rvs-marker-normal { background: var(--emerald); box-shadow: 0 0 5px rgba(0,229,160,.55); }
.rvs-marker-watch  { background: var(--amber);   box-shadow: 0 0 5px rgba(255,181,71,.55); }
.rvs-marker-alert  { background: var(--rose);    box-shadow: 0 0 5px rgba(255,79,109,.55); }
.rvs-marker-low    { background: var(--rose);    box-shadow: 0 0 5px rgba(255,79,109,.55); }
.rvs-marker-high   { background: var(--amber);   box-shadow: 0 0 5px rgba(255,181,71,.55); }

/* Fill bar — used for signal-level (percentile) bars */
.rvs-fill { height: 100%; border-radius: 4px; position: relative; z-index: 2; }
.rvs-fill-normal { background: linear-gradient(90deg, rgba(0,229,160,.45), var(--emerald)); }
.rvs-fill-watch  { background: linear-gradient(90deg, rgba(255,181,71,.45), var(--amber)); }
.rvs-fill-alert  { background: linear-gradient(90deg, rgba(255,79,109,.45), var(--rose)); }
.rvs-fill-low    { background: linear-gradient(90deg, rgba(255,79,109,.45), var(--rose)); }
.rvs-fill-high   { background: linear-gradient(90deg, rgba(255,181,71,.45), var(--amber)); }

.rvs-hint { font-size: 11px; color: var(--t3); margin-top: 5px; }

/* ── Z-score distribution chart ───────────────────────────────────────── */
/* Used by per-finding charts when stats are available and by the
   multi-signature deviation widget. Axis runs from −4σ to +4σ. The ±2σ
   "normal" band (≈ 95% of healthy) is shaded green; the |z|>3 area at the
   edges of the track shows in rose (alert). The patient marker is a vertical
   line coloured by its status. */
.rvs-zrow { /* container for per-finding z chart — same layout as rvs-row */ }

.rvs-ztrack {
  position: relative; height: 14px;
  background: rgba(255, 79, 109, 0.10);             /* rose tint for outer |z|>3 region */
  border: 1px solid rgba(255, 79, 109, 0.18);
  border-radius: 4px;
  overflow: visible;
  margin-bottom: 4px;
}
.rvs-ztrack-sm { height: 10px; }

/* Shaded distribution bands inside the track */
.rvs-zone {
  position: absolute; top: -1px; height: calc(100% + 2px);
  pointer-events: none; z-index: 1;
}
.rvs-zone-watch {
  background: rgba(255, 181, 71, 0.14);             /* amber: |z| between 2 and 3 */
  border-left:  1px solid rgba(255, 181, 71, 0.30);
  border-right: 1px solid rgba(255, 181, 71, 0.30);
}
.rvs-zone-normal {
  background: rgba(0, 229, 160, 0.18);              /* emerald: ±2σ healthy zone */
  border-left:  1px solid rgba(0, 229, 160, 0.40);
  border-right: 1px solid rgba(0, 229, 160, 0.40);
}

/* Axis lines: centre dashed line (z=0) and ±2σ tick lines */
.rvs-zaxis {
  position: absolute; top: -2px; height: calc(100% + 4px);
  width: 1px; z-index: 2; pointer-events: none;
}
.rvs-zaxis-center {
  left: 50%; transform: translateX(-50%);
  background: linear-gradient(to bottom, rgba(255,255,255,0.55) 50%, transparent 50%);
  background-size: 100% 4px;
}
.rvs-zaxis-tick {
  background: rgba(255, 255, 255, 0.22);
  transform: translateX(-50%);
}

/* Patient marker — coloured vertical line on the z-axis */
.rvs-zmarker {
  position: absolute; top: -4px;
  width: 3px; height: calc(100% + 8px);
  border-radius: 2px; z-index: 4;
  transform: translateX(-50%);
}
.rvs-zmarker-normal { background: var(--emerald); box-shadow: 0 0 5px rgba(0,229,160,.65); }
.rvs-zmarker-watch  { background: var(--amber);   box-shadow: 0 0 5px rgba(255,181,71,.65); }
.rvs-zmarker-alert  { background: var(--rose);    box-shadow: 0 0 5px rgba(255,79,109,.65); }
.rvs-zmarker-low    { background: var(--rose);    box-shadow: 0 0 5px rgba(255,79,109,.65); }
.rvs-zmarker-high   { background: var(--amber);   box-shadow: 0 0 5px rgba(255,181,71,.65); }
/* Direction-aware: protective deviations (clinically beneficial) */
.rvs-zmarker-protective_watch   { background: var(--cyan); box-shadow: 0 0 5px rgba(34,211,238,.65); }
.rvs-zmarker-protective_extreme { background: var(--cyan); box-shadow: 0 0 6px rgba(34,211,238,.85); width: 4px; }
.rvs-protective_watch   { color: var(--cyan); }
.rvs-protective_extreme { color: var(--cyan); }

/* Axis labels below the track */
.rvs-zaxis-labels {
  display: flex; justify-content: space-between; align-items: center;
  font-size: 10px; color: var(--t3);
  margin-top: 2px;
}
.rvs-zlbl-c { font-style: italic; color: var(--t2); }

/* Multi-signature widget */
.rvs-sig-group { margin-bottom: 14px; }
.rvs-sig-group:last-child { margin-bottom: 0; }
.rvs-sig-group-hd {
  font-size: 11px; font-weight: 700; text-transform: uppercase;
  letter-spacing: .07em; color: var(--cyan);
  margin: 6px 0 8px;
}
.rvs-zrows { display: flex; flex-direction: column; gap: 7px; }
.rvs-zrow-multi {
  display: grid;
  grid-template-columns: minmax(150px, 1.4fr) minmax(140px, 3fr) auto;
  gap: 10px; align-items: center;
}
.rvs-zrow-lbl { font-size: 12px; color: var(--t1); }
.rvs-zrow-lbl-name { font-weight: 600; }
.rvs-zrow-lbl-sub  { font-size: 10.5px; color: var(--t3); margin-top: 2px; line-height: 1.35; }

/* Legend caption above the per-signature deviation rows in the Cancer
   Surveillance card. Explains the direction-aware colour scheme. */
.rvs-zlegend {
  font-size: 11.5px; color: var(--t3); line-height: 1.55;
  padding: 8px 12px; background: var(--elevated);
  border: 1px solid var(--border); border-radius: 6px;
  margin-bottom: 4px;
}
.rvs-zlegend strong { color: var(--t2); font-weight: 600; }
.rvs-zrow-val {
  font-size: 11px; font-weight: 600; font-variant-numeric: tabular-nums;
  white-space: nowrap; min-width: 64px; text-align: right;
}
.rvs-zaxis-labels-multi { margin-top: 10px; padding: 0 4px; }

/* ── Age comparison widget ─────────────────────────────────────────────── */
.rvs-age-card { }

.rvs-age-stats {
  display: grid; grid-template-columns: 1fr 1fr 2fr;
  gap: 16px; margin-bottom: 22px;
}
.rvs-age-stat-lbl {
  font-size: 11px; font-weight: 700; text-transform: uppercase;
  letter-spacing: .07em; color: var(--t3); margin-bottom: 6px;
}
.rvs-age-stat-val {
  font-size: 38px; font-weight: 800; line-height: 1; letter-spacing: -.03em;
}
.rvs-age-stat-unit { font-size: 14px; font-weight: 400; color: var(--t3); letter-spacing: 0; }
.rvs-age-stat-delta {
  font-size: 18px; font-weight: 700; line-height: 1.2; margin-bottom: 5px;
}
.rvs-age-stat-sub { font-size: 12px; color: var(--t2); line-height: 1.45; }

/* Ruler */
.rvs-age-ruler {
  position: relative; height: 62px;
  margin: 0 10px 4px;
}
.rvs-age-track-bg {
  position: absolute; top: 29px; left: 0; right: 0;
  height: 4px; background: var(--elevated); border-radius: 2px;
}
.rvs-age-connector {
  position: absolute; top: 29px; height: 4px; border-radius: 2px;
}
.rvs-age-conn-normal { background: var(--emerald); opacity: .7; }
.rvs-age-conn-watch  { background: var(--amber);   opacity: .7; }
.rvs-age-conn-alert  { background: var(--rose);    opacity: .7; }

.rvs-age-dot {
  position: absolute; top: 22px;
  width: 16px; height: 16px; border-radius: 50%;
  transform: translateX(-50%); z-index: 3;
  border: 2px solid var(--card);
}
.rvs-age-dot-real                { background: var(--cyan); }
.rvs-age-dot-immune.rvs-age-dot-normal { background: var(--emerald); box-shadow: 0 0 8px rgba(0,229,160,.5); }
.rvs-age-dot-immune.rvs-age-dot-watch  { background: var(--amber);   box-shadow: 0 0 8px rgba(255,181,71,.5); }
.rvs-age-dot-immune.rvs-age-dot-alert  { background: var(--rose);    box-shadow: 0 0 8px rgba(255,79,109,.5); }

.rvs-age-lbl-year {
  position: absolute; bottom: calc(100% + 5px); left: 50%;
  transform: translateX(-50%);
  font-size: 12px; font-weight: 700; white-space: nowrap;
}
.rvs-age-lbl-text {
  position: absolute; top: calc(100% + 8px); left: 50%;
  transform: translateX(-50%);
  font-size: 10px; color: var(--t3); white-space: nowrap;
  text-transform: uppercase; letter-spacing: .04em;
}

/* Signals grid */
.rvs-signals {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(150px, 1fr));
  gap: 14px;
}
.rvs-signal        { display: flex; flex-direction: column; gap: 6px; }
.rvs-signal-label  { font-size: 12px; color: var(--t2); font-weight: 500; }
.rvs-signal-val    { font-size: 12px; font-weight: 700; }

/* ── NARRATIVE SECTION CARDS (lay mode) ─────────────────────────────────────── */
.nls-stack {
  display: grid; grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 12px; margin-bottom: 28px;
}
.nls-stack .nls-actions-card,
.nls-stack .nls-bottomline { grid-column: 1 / -1; }

.nls-card {
  background: var(--card); border: 1px solid rgba(255,255,255,.2);
  border-radius: var(--r); overflow: hidden;
  border-left: 3px solid var(--border);
  display: flex; flex-direction: column;
}
.nls-card.sig-high     { border-left-color: var(--rose); }
.nls-card.sig-moderate { border-left-color: var(--amber); }
.nls-card.sig-low      { border-left-color: var(--cyan); }
.nls-card.sig-normal   { border-left-color: var(--emerald); }
.nls-actions-card      { border-left-color: var(--rose); }

.nls-head {
  display: flex; align-items: center; gap: 10px;
  padding: 12px 20px; background: var(--elevated);
  border-bottom: 1px solid var(--border);
}
.nls-emoji     { font-size: 15px; line-height: 1; flex-shrink: 0; }
.nls-title-txt { font-size: 11px; font-weight: 700; text-transform: uppercase; letter-spacing: .08em; color: var(--t1); flex: 1; }

.nls-sig {
  font-size: 10px; font-weight: 700; text-transform: uppercase;
  letter-spacing: .06em; padding: 3px 9px; border-radius: 10px; white-space: nowrap;
}
.nls-sig-high     { background: rgba(244,63,94,.15);  color: var(--rose);    border: 1px solid rgba(244,63,94,.3); }
.nls-sig-moderate { background: rgba(251,191,36,.12); color: var(--amber);   border: 1px solid rgba(251,191,36,.3); }
.nls-sig-low      { background: rgba(34,211,238,.1);  color: var(--cyan);    border: 1px solid rgba(34,211,238,.25); }
.nls-sig-normal   { background: rgba(52,211,153,.1);  color: var(--emerald); border: 1px solid rgba(52,211,153,.25); }

.nls-body { padding: 18px 22px; display: flex; flex-direction: column; gap: 14px; flex: 1 1 auto; }

.nls-p { font-size: 14px; line-height: 1.8; color: var(--t2); margin: 0; max-width: 72ch; }
.nls-p strong { color: var(--t1); font-weight: 600; }

/* Table within section card */
.nls-table-wrap { overflow-x: auto; }
.nls-table { width: 100%; border-collapse: collapse; font-size: 13px; }
.nls-table th {
  background: var(--elevated); color: var(--t3);
  font-size: 10px; font-weight: 700; text-transform: uppercase;
  letter-spacing: .06em; padding: 8px 12px; text-align: left;
  border-bottom: 1px solid var(--border);
}
.nls-table td { padding: 9px 12px; color: var(--t2); border-bottom: 1px solid var(--border); }
.nls-table tr:last-child td { border-bottom: none; }
.nls-table tr:hover td { background: rgba(255,255,255,.02); }
.nls-table .rnst-ok { color: var(--emerald); font-weight: 600; }
.nls-table .rnst-hi { color: var(--rose);    font-weight: 600; }
.nls-table .rnst-lo { color: var(--cyan);    font-weight: 600; }
.nls-table .rnst-md { color: var(--amber);   font-weight: 600; }
.nls-table .rnst-ok::before,
.nls-table .rnst-hi::before,
.nls-table .rnst-lo::before,
.nls-table .rnst-md::before { content: '●'; font-size: 7px; margin-right: 5px; vertical-align: middle; }
.nls-table .rnst-ok::before { color: var(--emerald); }
.nls-table .rnst-hi::before { color: var(--rose); }
.nls-table .rnst-lo::before { color: var(--cyan); }
.nls-table .rnst-md::before { color: var(--amber); }

/* Callout box */
.nls-callout {
  background: rgba(0,212,255,.06);
  border-top: 1px solid var(--border);
  padding: 14px 22px;
}
.nls-callout-lbl { font-size: 10px; font-weight: 700; text-transform: uppercase; letter-spacing: .1em; color: var(--cyan); margin-bottom: 4px; }
.nls-callout-txt { font-size: 13.5px; color: var(--t1); line-height: 1.65; }

/* Action items */
.nls-actions-list { padding: 16px 22px; display: flex; flex-direction: column; gap: 9px; }
.nls-action {
  display: flex; align-items: flex-start; gap: 12px;
  padding: 11px 14px; border-radius: 8px;
  background: var(--elevated); border: 1px solid var(--border);
}
.nls-action-num {
  min-width: 22px; height: 22px; border-radius: 50%;
  background: var(--rose); color: #fff;
  font-size: 11px; font-weight: 700;
  display: flex; align-items: center; justify-content: center;
  flex-shrink: 0; margin-top: 1px;
}
.nls-action-txt { font-size: 13.5px; color: var(--t1); line-height: 1.6; }

/* Bottom line */
.nls-bottomline {
  display: flex; align-items: flex-start; gap: 12px;
  border: 1px solid var(--border); border-left: 3px solid var(--amber);
  border-radius: var(--r); padding: 14px 20px;
  background: var(--elevated);
}
.nls-bottomline-lbl { font-size: 10px; font-weight: 700; text-transform: uppercase; letter-spacing: .1em; color: var(--amber); white-space: nowrap; padding-top: 2px; }
.nls-bottomline-txt { font-size: 14px; color: var(--t1); line-height: 1.65; }

.nls-reviewed {
  display: flex; align-items: flex-start; gap: 12px;
  border: 1px solid var(--border); border-left: 3px solid var(--cyan);
  border-radius: var(--r); padding: 14px 20px;
  background: linear-gradient(180deg, rgba(34,211,238,0.04), rgba(34,211,238,0.01));
  margin-top: 14px;
}
.nls-reviewed-icon { flex-shrink: 0; margin-top: 2px; }
.nls-reviewed-body { display: flex; flex-direction: column; gap: 4px; }
.nls-reviewed-lbl  { font-size: 10px; font-weight: 700; text-transform: uppercase; letter-spacing: .1em; color: var(--cyan); }
.nls-reviewed-txt  { font-size: 13.5px; color: var(--t2); line-height: 1.65; }
.nls-reviewed-txt strong { color: var(--t1); font-weight: 600; }

/* ── RESPONSIVE ──────────────────────────────────────────────────────────────── */
/* All responsive rules MUST live at the end of the file so they override base styles */

/* Hamburger button — hidden on desktop, shown on mobile */
.sb-toggle {
  display: none; align-items: center; justify-content: center;
  width: 34px; height: 34px; flex-shrink: 0;
  background: var(--card); border: 1px solid var(--border);
  border-radius: 7px; cursor: pointer; color: var(--t2);
  transition: all .18s;
}
.sb-toggle:hover { border-color: var(--glow); color: var(--t1); }

/* Sidebar backdrop overlay */
#sb-overlay {
  display: none; position: fixed; inset: 0;
  background: rgba(0,0,0,0.55); z-index: 150;
  backdrop-filter: blur(2px);
}
#sb-overlay.visible { display: block; }

/* ── Home page layout (3:1 main / order-side) ───────────────────────────── */
.home-layout {
  display: grid; grid-template-columns: 3fr 1fr; gap: 20px;
  align-items: start;
}
.home-main { min-width: 0; }
.home-side { display: flex; flex-direction: column; gap: 14px; }

/* Genome Portrait card — sits in .home-side above the RNA Test order box. */
.home-portrait {
  display: block; text-decoration: none; color: inherit;
  background: var(--card); border: 1px solid var(--border);
  border-left: 3px solid var(--violet);
  border-radius: var(--r);
  padding: 12px 12px 6px;
  transition: border-color .18s, transform .18s;
}
.home-portrait:hover { border-color: var(--violet); transform: translateY(-1px); }
.home-portrait-lbl {
  font-family: 'Outfit', sans-serif;
  font-size: 11px; font-weight: 700; letter-spacing: .08em;
  text-transform: uppercase; color: var(--violet);
  margin-top: 10px; text-align: center;
}
.home-portrait-img {
  display: block; width: 100%; height: auto;
  border-radius: 8px;
  background: var(--bg);
}

.order-box {
  background: var(--card); border: 1px solid var(--border);
  border-left: 3px solid var(--border); border-radius: var(--r);
  padding: 16px 16px 14px;
  display: flex; flex-direction: column; gap: 8px;
}
.order-box-violet  { border-left-color: var(--violet); }
.order-box-cyan    { border-left-color: var(--cyan); }
.order-box-emerald { border-left-color: var(--emerald); }

.order-box-hd { display: flex; align-items: center; gap: 8px; }
.order-ico { flex-shrink: 0; }
.order-box-violet  .order-ico { color: var(--violet); }
.order-box-cyan    .order-ico { color: var(--cyan); }
.order-box-emerald .order-ico { color: var(--emerald); }
.order-title {
  font-family: 'Outfit', sans-serif;
  font-size: 14.5px; font-weight: 700; color: var(--t1); letter-spacing: .01em;
}
.order-desc { font-size: 12px; color: var(--t2); line-height: 1.5; }

.order-btn {
  margin-top: 4px;
  padding: 9px 14px; border-radius: 8px;
  font-size: 12.5px; font-weight: 700; letter-spacing: .03em;
  cursor: pointer; transition: all .18s;
  border: 1px solid transparent;
  width: 100%;
}
.order-box-violet  .order-btn { background: var(--violet);  color: #fff; }
.order-box-cyan    .order-btn { background: var(--cyan);    color: #fff; }
.order-box-emerald .order-btn { background: var(--emerald); color: #fff; }
.order-box-violet  .order-btn:hover:not(:disabled)  { background: var(--violet-d);  color: #fff; border-color: var(--violet); }
.order-box-cyan    .order-btn:hover:not(:disabled)  { background: var(--cyan-d);    color: #fff; border-color: var(--cyan); }
.order-box-emerald .order-btn:hover:not(:disabled)  { background: var(--emerald-d); color: #fff; border-color: var(--emerald); }
.order-btn-soon {
  background: var(--elevated) !important; color: var(--t1) !important;
  border-color: var(--border) !important;
  cursor: default;
}

/* ── Home: Risk × Activity quadrant chart ──────────────────────────────── */
.home-main { display: flex; flex-direction: column; gap: 16px; }

.hq-card { padding: 22px 24px; }
.hq-hd { display: flex; align-items: flex-start; justify-content: space-between; gap: 14px; margin-bottom: 18px; }
.hq-title { font-family:'Outfit', sans-serif; font-size: 17px; font-weight: 700; color: var(--t1); }
.hq-sub   { font-size: 12.5px; color: var(--t2); margin-top: 4px; line-height: 1.5; }
.hq-status-pill {
  flex-shrink: 0; align-self: flex-start;
  padding: 6px 12px; border-radius: 20px; font-size: 11.5px; font-weight: 700;
  letter-spacing: .04em; text-transform: uppercase;
  border: 1px solid; background: rgba(255,255,255,0.02);
}

.hq-grid-wrap {
  display: grid;
  grid-template-columns: 28px 1fr;
  grid-template-rows: 1fr 24px;
  gap: 6px;
  margin-bottom: 18px;
  min-width: 0;
}
.hq-y-axis {
  display: flex; flex-direction: column; align-items: center; justify-content: center;
  padding: 6px 0;
}
.hq-y-name {
  writing-mode: vertical-rl; transform: rotate(180deg);
  font-size: 10.5px; font-weight: 700; letter-spacing: .12em; text-transform: uppercase;
  color: var(--t3);
}
.hq-x-axis {
  display: flex; align-items: center; justify-content: center;
  padding: 4px 8px 0;
}
.hq-x-name {
  font-size: 10.5px; font-weight: 700; letter-spacing: .12em; text-transform: uppercase;
  color: var(--t3);
}
.hq-axis-tick {
  font-size: 9.5px; color: var(--t3); letter-spacing: .08em; text-transform: uppercase;
}

/* Axis ticks anchored on the crosshairs inside the chart */
.hq-x-tick, .hq-y-tick {
  position: absolute;
  font-size: 9px; font-weight: 600; color: var(--t3);
  letter-spacing: .08em; text-transform: uppercase;
  padding: 2px 6px; background: var(--bg); border-radius: 3px;
  z-index: 1;
}
.hq-x-tick { top: 50%; transform: translateY(-50%); }
.hq-x-tick-low  { left: 6px; }
.hq-x-tick-high { right: 6px; }
.hq-y-tick { left: 50%; transform: translateX(-50%); }
.hq-y-tick-active { top: 6px; }
.hq-y-tick-calm   { bottom: 6px; }
.hq-arr {
  display: inline-block; vertical-align: middle;
  color: var(--t2);
  margin: 0 8px;
  flex-shrink: 0;
}
.hq-chart {
  position: relative; aspect-ratio: 16 / 9;
  background: var(--bg); border-radius: 10px; overflow: hidden;
  min-height: 220px;
}
.hq-quad { position: absolute; width: 50%; height: 50%; }
.hq-quad-tl { top: 0;     left: 0;     background: rgba(34,211,238,.10);  } /* cyan    — Investigate Triggers */
.hq-quad-tr { top: 0;     right: 0;    background: rgba(244,63,94,.10);   } /* rose    — Priority Review */
.hq-quad-bl { bottom: 0;  left: 0;     background: rgba(52,211,153,.10);  } /* emerald — All Clear */
.hq-quad-br { bottom: 0;  right: 0;    background: rgba(139,92,246,.10);  } /* violet  — Risk Managed */
.hq-axis    { position: absolute; background: rgba(255,255,255,0.10); }
.hq-axis-h  { left: 0; right: 0; top: 50%; height: 1px; }
.hq-axis-v  { top: 0; bottom: 0; left: 50%; width: 1px; }
.hq-quad-lbl {
  position: absolute; font-size: 10.5px; font-weight: 700; letter-spacing: .04em;
  text-transform: uppercase; padding: 4px 8px; pointer-events: none;
  color: var(--t2); opacity: .85;
}
.hq-quad-lbl-tl { top: 8px; left: 10px;   color: var(--cyan); }
.hq-quad-lbl-tr { top: 8px; right: 10px;  color: var(--rose); }
.hq-quad-lbl-bl { bottom: 8px; left: 10px;   color: var(--emerald); }
.hq-quad-lbl-br { bottom: 8px; right: 10px;  color: var(--violet); }

.hq-dot {
  position: absolute; width: 14px; height: 14px; border-radius: 50%;
  transform: translate(-50%, 50%);
  border: 2px solid var(--bg);
  z-index: 3;
}
.hq-dot-pulse {
  position: absolute; width: 14px; height: 14px; border-radius: 50%;
  transform: translate(-50%, 50%);
  z-index: 2; opacity: .6;
  animation: hq-pulse 2.4s ease-out infinite;
}
@keyframes hq-pulse {
  0%   { transform: translate(-50%, 50%) scale(1);   opacity: .55; }
  100% { transform: translate(-50%, 50%) scale(3.2); opacity: 0; }
}

.hq-readout { display: flex; flex-direction: column; gap: 8px; padding: 14px 16px; background: var(--elevated); border-radius: 10px; margin-bottom: 14px; }
.hq-readout-row { display: flex; align-items: baseline; gap: 14px; flex-wrap: wrap; }
.hq-readout-lbl { font-size: 10.5px; font-weight: 700; letter-spacing: .1em; text-transform: uppercase; color: var(--t3); min-width: 130px; }
.hq-readout-val { font-size: 15px; font-weight: 700; color: var(--t1); font-family:'Outfit', sans-serif; }
.hq-readout-meta { font-size: 12px; color: var(--t3); margin-left: auto; }

.hq-explain { font-size: 13px; color: var(--t2); line-height: 1.6; padding-left: 2px; }
.hq-empty   { font-size: 13px; color: var(--t3); line-height: 1.6; padding: 16px 4px; }

/* ── Home: status cards (DNA / RNA snapshots) ──────────────────────────── */
.hs-grid { display: grid; grid-template-columns: 1fr 1fr; gap: 12px; }
.hs-card {
  display: block; text-decoration: none; color: inherit;
  background: var(--card); border: 1px solid var(--border); border-radius: var(--r);
  border-left: 3px solid var(--border);
  padding: 16px 18px;
  transition: border-color .18s, transform .18s;
}
.hs-card:hover { border-color: var(--glow); transform: translateY(-1px); }
.hs-dna { border-left-color: var(--violet); }
.hs-rna { border-left-color: var(--cyan); }
.hs-card-hd { display: flex; align-items: center; gap: 8px; margin-bottom: 12px; }
.hs-card-ttl { font-family:'Outfit', sans-serif; font-size: 14px; font-weight: 700; color: var(--t1); flex: 1; }
.hs-card-pill {
  font-size: 10px; font-weight: 700; letter-spacing: .06em; text-transform: uppercase;
  padding: 3px 9px; border-radius: 4px;
}
.hs-pill-ok      { background: rgba(52,211,153,.12); color: var(--emerald); }
.hs-pill-pending { background: rgba(148,163,184,.1); color: var(--t3); }
.hs-card-meta { display: flex; flex-direction: column; gap: 5px; margin-bottom: 12px; }
.hs-meta-lbl { font-size: 10.5px; font-weight: 600; letter-spacing: .06em; text-transform: uppercase; color: var(--t3); margin-right: 4px; }
.hs-meta-val { font-size: 13px; font-weight: 600; color: var(--t1); }
.hs-card-empty { font-size: 12px; color: var(--t3); font-style: italic; margin-bottom: 12px; }
.hs-card-cta { font-size: 11.5px; font-weight: 600; color: var(--cyan); letter-spacing: .02em; }
.hs-dna .hs-card-cta { color: var(--violet); }
.hs-card-cta-muted { color: var(--t3) !important; }

/* ── Home: top action items ────────────────────────────────────────────── */
.ha-card { padding: 18px 22px; }
.ha-hd { display: flex; align-items: center; gap: 10px; margin-bottom: 12px; }
.ha-title { font-family:'Outfit', sans-serif; font-size: 14px; font-weight: 700; color: var(--t1); }
.ha-sub { font-size: 11.5px; color: var(--t3); }
.ha-list { list-style: none; margin: 0; padding: 0; display: flex; flex-direction: column; gap: 10px; }
.ha-item { display: flex; align-items: flex-start; gap: 10px; padding: 10px 12px; background: var(--elevated); border-radius: 8px; border: 1px solid var(--border); }
.ha-num {
  flex-shrink: 0; width: 22px; height: 22px; border-radius: 50%;
  display: inline-flex; align-items: center; justify-content: center;
  font-size: 11px; font-weight: 700; color: var(--t1);
  background: rgba(251,191,36,.18); border: 1px solid rgba(251,191,36,.4);
}
.ha-source {
  flex-shrink: 0; font-size: 9.5px; font-weight: 700; letter-spacing: .1em; text-transform: uppercase;
  padding: 3px 7px; border-radius: 4px; align-self: center;
}
.ha-source-dna { background: rgba(139,92,246,.15); color: var(--violet); }
.ha-source-rna { background: rgba(34,211,238,.12); color: var(--cyan); }
.ha-text { font-size: 13px; color: var(--t2); line-height: 1.55; }

/* ── 900px: tablets landscape ── */
@media (max-width: 900px) {
  .sg4 { grid-template-columns: repeat(2,1fr); }
  .three-col { grid-template-columns: repeat(2,1fr); }
  main { padding: 22px 20px; }
  .rna-test-meta { grid-template-columns: repeat(3,1fr); }
  .rsum-grid     { grid-template-columns: 1fr; }
  .rna-sections  { grid-template-columns: 1fr; }
  .nls-stack { grid-template-columns: 1fr; }
  .decon-stats { grid-template-columns: repeat(3, 1fr); }
  .pp-stats    { grid-template-columns: repeat(2, 1fr); }
  .home-layout { grid-template-columns: 1fr; }
  .home-side { flex-direction: row; flex-wrap: wrap; }
  .home-side .order-box,
  .home-side .hs-card,
  .home-side .home-portrait { flex: 1 1 240px; }
  .hq-readout-row { flex-direction: column; align-items: flex-start; gap: 4px; }
  .hq-readout-meta { margin-left: 0; }
  .hq-chart { min-height: 0; }
  .hq-card { padding: 18px 16px; }
}

/* ── 768px: tablets portrait / large phones — sidebar goes off-canvas, all grids single column ── */
@media (max-width: 768px) {
  #sb { transform: translateX(-100%); transition: transform .25s cubic-bezier(0.4,0,0.2,1); z-index: 200; }
  #sb.open { transform: translateX(0); }
  header { padding: 0 14px; gap: 10px; }
  .hdate { display: none; }
  .sb-toggle { display: flex; }
  main { margin-left: 0; padding: 16px 14px; }
  .sg2 { grid-template-columns: 1fr; }
  .sg3 { grid-template-columns: 1fr; }
  .sg4 { grid-template-columns: 1fr; }
  .sg5 { grid-template-columns: 1fr; }
  .two-col { grid-template-columns: 1fr; }
  .three-col { grid-template-columns: 1fr; }
  .syn-grid { grid-template-columns: 1fr; }
  .rna-visual-summary { grid-template-columns: 1fr; }
  .card { padding: 14px; overflow-x: auto; }
  .rtable { overflow-x: auto; }
  .gene-card { padding: 12px; }
  .stat-val { font-size: 22px; }
  .vcard-hint { display: none; }
  .alert { padding: 12px 14px; }
  .vcard-summary { padding: 11px 14px; }
  .vcard-body { padding: 14px; }
  .vcard-meta { padding: 11px 14px; }
  .rna-test-meta { grid-template-columns: repeat(2,1fr); }
  .rna-meta-val { font-size: 14px; }
  .decon-stats { grid-template-columns: repeat(2, 1fr); }
  .decon-card { padding: 14px 16px; }
  .pp-stats   { grid-template-columns: repeat(2, 1fr); }
  .pp-card    { padding: 14px 16px; }
  .fastp-card { padding: 14px 16px; }
  .fastp-row  { grid-template-columns: 1fr; gap: 4px; }
  .fastp-row-meta { font-size: 11px; }
  .cqc-card   { padding: 14px 16px; }
  .cqc-stats  { grid-template-columns: 1fr; }
  .cqc-cat    { grid-template-columns: 14px 1fr auto auto; gap: 8px; }
  .cqc-cat-reads { font-size: 11px; }
  .cqc-taxa-row  { grid-template-columns: 28px 1fr auto; gap: 8px; }
  .cqc-taxa-row .cqc-taxa-pct { display: none; }
  .rvs-zrow-multi { grid-template-columns: minmax(100px, 1fr) minmax(120px, 2fr) auto; gap: 8px; }
  .rvs-zrow-lbl { font-size: 11px; }
  .rvs-zrow-val { font-size: 10px; min-width: 56px; }
  .rsum-grid    { grid-template-columns: 1fr; }
  .rna-sections { grid-template-columns: 1fr; }
  .rsec-pills   { flex-direction: column; gap: 10px; }
  .rsec-pillbox { min-width: 0; }
}

/* ── 480px: phones — spacing and font reductions ── */
@media (max-width: 480px) {
  main { padding: 12px 10px; }
  .card { padding: 12px; }
  .stat-val { font-size: 20px; }
  .stat-box { padding: 12px 14px; }
  .ph-title { font-size: 20px; }
  .hid { display: none; }
  .auth-box { padding: 24px 18px; }
  .auth-features { grid-template-columns: 1fr; }
  .alert { flex-direction: column; gap: 8px; }
  .vcard-summary { flex-wrap: wrap; gap: 6px; }
  .vcard-condition { min-width: 100%; order: 3; white-space: normal; }
  .rvs-signals               { grid-template-columns: 1fr 1fr; }
  .rvs-age-stats             { grid-template-columns: 1fr 1fr; }
  .rvs-age-stats > :last-child { grid-column: 1 / -1; }
  .rvs-age-stat-val          { font-size: 30px; }
  .pp-det-list               { grid-template-columns: 1fr; }
  .rna-verdict               { flex-wrap: wrap; gap: 10px; }
  .rna-verdict-sep           { display: none; }
  .rna-verdict-desc          { width: 100%; padding-left: 27px; }
}

/* ── DNA section mode switching ─────────────────────────────────────────────── */

#dna-wrap[data-mode="lay"]      [data-clinical] { display: none; }
#dna-wrap[data-mode="clinical"] [data-lay]      { display: none; }

.dna-mode-btn {
  display: inline-flex; align-items: center; gap: 7px;
  padding: 7px 16px; border-radius: 8px; font-size: 12px; font-weight: 600;
  border: 1px solid var(--border); background: var(--elevated);
  color: var(--t2); cursor: pointer; transition: all .18s; letter-spacing: .02em;
  margin-left: auto; flex-shrink: 0;
}
.dna-mode-btn:hover:not(:disabled) { border-color: var(--cyan); color: var(--cyan); }
.dna-mode-btn:disabled { opacity: 0.45; cursor: default; }

/* Generating spinner */
.dna-gen-spinner {
  width: 20px; height: 20px; border-radius: 50%; flex-shrink: 0;
  border: 2px solid var(--border); border-top-color: var(--cyan);
  animation: dna-spin .8s linear infinite;
}
@keyframes dna-spin { to { transform: rotate(360deg); } }

/* Plain language headline (bolder intro line) */
.nls-headline {
  font-size: 15px; font-weight: 600; color: var(--t1); margin: 0 0 4px;
  line-height: 1.5;
}

/* sig-badge variants for DNA nls cards */
.sig-badge-high     { background: rgba(255,79,109,.15); color: var(--rose); }
.sig-badge-moderate { background: rgba(255,179,0,.12);  color: var(--amber); }
.sig-badge-low      { background: rgba(0,212,255,.10);  color: var(--cyan); }
.sig-badge-normal   { background: rgba(52,211,153,.10); color: var(--emerald); }